DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and Mst1

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_038936729.1	Gene:	Mst1 / 24566	RGDID:	3114	Length:	747	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	96/312 - (30%)
Similarity:	140/312 - (44%)	Gaps:	50/312 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 APHQTLAQQFADVVD---------VVDP-------AEQSIKAVRPPKSRNQCTAKQNCFCG---- 69
            |||..|...|....|         .:||       |.:.....:||...:.....|...||
  Rat   449 APHAGLEANFCRNPDGDSHGPWCYTLDPETLFDYCALKRCDDDQPPSILDPPVQVQFEKCGKRVD 513

  Fly    70 TPNVNRIVGGQQVRSNKYPWTAQL--VKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQIT--- 129
            ..|..|:|||....|   |||..|  .:|:|    ||||||:.:::||||..|:....|.:|
  Rat   514 QSNRLRVVGGHPGNS---PWTVSLRNRQGQH----FCGGSLVKEQWVLTARQCIWSCHDPLTGYE 571

  Fly   130 IRLLQIDRSSRDPGIVR----KVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEAN 190
            :.|..|:::.: ||...    .|.:|...|      ..:.:.|||||.||.|..::..:|||...
  Rat   572 VWLGTINQNPQ-PGEANLQRVSVAKTVCGP------AGSQLVLLKLERPVILNHHVARICLPPEQ 629

  Fly   191 HNF-DGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQCRQTRYKDKIAEVMLCA-GLVQQGGK 253
            :.. .|....:||||..| |...|..|....:.||::.:| ..:|:.::.|..:|. ||:...|
  Rat   630 YVVPPGTNCEIAGWGESK-GTSNSTVLHVAKMKVISSQEC-NVKYRRRVQESEICTEGLLAPTG- 691

  Fly   254 DACQGDSGGPL-IVNEGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRK 304
             ||:||.|||| ......:.|.|::.....||:...|.::.|||.|:|||.|
  Rat   692 -ACEGDYGGPLACYTHDCWVLQGLIIPNRVCARPRWPAIFTRVSVFVDWINK 742

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	78/238 (33%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	80/241 (33%)
Mst1	XP_038936729.1	PAN_1	32..111	CDD:394981
		KR	116..196	CDD:214527
		KR	199..276	CDD:214527
		KR	321..403	CDD:214527
		KR	408..490	CDD:214527	9/40 (23%)
		Tryp_SPc	520..743	CDD:238113	80/241 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910