DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	97/280 - (34%)
Similarity:	136/280 - (48%)	Gaps:	60/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 NQCTAKQ----NCF-CGTPNV---NRIVGGQQVRSNKYPWTAQL-VKGRHYPRLFCGGSLINDRY 113
            :.|:::.    .|. ||..:|   :|||||.......:||...| |:|.|    .||||:|...:
  Rat   228 DSCSSRMVVSLRCIECGVRSVRRQSRIVGGSTASPGDWPWQVSLHVQGIH----VCGGSIITPEW 288

  Fly   114 VLTAAHCV-----------------------HGNRDQITIRLLQIDRSSRDPGIVRKVVQTTVHP 155
            ::||||||                       :|:|.|                 |.||:.   ||
  Rat   289 IVTAAHCVEEPLSSPRYWTAFAGILKQSLMFYGSRHQ-----------------VEKVIS---HP 333

  Fly   156 NYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANHNFD-GKTAVVAGWGLIKEGGVTSNYLQEV 219
            |||.....||:||:||::|:.....::|||||......| .:...::|||...|.|.||:.|...
  Rat   334 NYDSKTKNNDIALMKLQTPLAFNDVVKPVCLPNPGMMLDLAQECWISGWGATYEKGKTSDVLNAA 398

  Fly   220 NVPVITNAQCRQTR-YKDKIAEVMLCAGLVQQGGKDACQGDSGGPLIVNEGR-YKLAGVVSFGYG 282
            .||:|..::|.... |.:.|...|:|||.: ||..|:|||||||||:..:.. :.|.|..|:|.|
  Rat   399 MVPLIEPSKCNSKYIYNNLITPAMICAGFL-QGSVDSCQGDSGGPLVTLKNEIWWLIGDTSWGSG 462

  Fly   283 CAQKNAPGVYARVSKFLDWI 302
            ||:...||||..|:.|.|||
  Rat   463 CAKAYRPGVYGNVTVFTDWI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	90/253 (36%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	91/254 (36%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:292133	4/18 (22%)
		Tryp_SPc	253..482	CDD:214473	90/253 (36%)
		Tryp_SPc	254..485	CDD:238113	91/254 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.860