DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and Mst1

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	293	Identity:	91/293 - (31%)
Similarity:	130/293 - (44%)	Gaps:	74/293 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VVDPAEQSIKAVRPPKSRNQCTAKQNCF--CG----TPNVNRIVGGQQVRSNKYPWTAQL--VKG 96
            ::||.:|.:                  |  ||    ..|..|:|||....|   |||..|  .:|
Mouse   465 ILDPPDQVV------------------FEKCGKRVDKSNKLRVVGGHPGNS---PWTVSLRNRQG 508

  Fly    97 RHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIRLLQIDRSSRDPGIVRKVVQTTVHPNYDP-- 159
            :|    ||||||:.:::||||..|:.               |..:|....:|...|::.|..|
Mouse   509 QH----FCGGSLVKEQWVLTARQCIW---------------SCHEPLTGYEVWLGTINQNPQPGE 554

  Fly   160 ---NRIV----------NDVALLKLESPVPLTGNMRPVCLPEANHNF-DGKTAVVAGWGLIKEGG 210
               .|:.          :.:.|||||.||.|..::..:|||...:.. .|....:||||   |..
Mouse   555 ANLQRVPVAKAVCGPAGSQLVLLKLERPVILNHHVALICLPPEQYVVPPGTKCEIAGWG---ESI 616

  Fly   211 VTSN--YLQEVNVPVITNAQCRQTRYKDKIAEVMLCA-GLVQQGGKDACQGDSGGPL-IVNEGRY 271
            .|||  .|...::.||:|.:| .|:|:..|.|..:|. |||...|  ||:||.|||| ......:
Mouse   617 GTSNNTVLHVASMNVISNQEC-NTKYRGHIQESEICTQGLVVPVG--ACEGDYGGPLACYTHDCW 678

  Fly   272 KLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRK 304
            .|.|::.....||:...|.::.|||.|:|||.|
Mouse   679 VLQGLIIPNRVCARPRWPAIFTRVSVFVDWINK 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	81/248 (33%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	83/251 (33%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527
		Tryp_SPc	488..709	CDD:214473	81/248 (33%)
		Tryp_SPc	489..712	CDD:238113	83/251 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910