DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	259	Identity:	105/259 - (40%)
Similarity:	145/259 - (55%)	Gaps:	29/259 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 QCTAKQNCFCGT-----PNVNRIVGGQQVRSNKYPWTAQL-VKGRHYPRLFCGGSLINDRYVLTA 117
            :|:|     |||     |   |||||......::||...| .:|.|    .||||:|...:::||
Mouse   225 KCSA-----CGTRTGYSP---RIVGGNMSSLTQWPWQVSLQFQGYH----LCGGSIITPLWIVTA 277

  Fly   118 AHCV----HGNRDQITIRLLQIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLT 178
            ||||    |.....:.:.|:.:..|.....:|.|::   .|..|.|.|:.||:||:||..|:...
Mouse   278 AHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKII---YHSKYKPKRLGNDIALMKLSEPLTFD 339

  Fly   179 GNMRPVCLPEANHNF-DGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQC-RQTRYKDKIAEV 241
            ..::|:|||.:..|| |||....:|||..::||..|..|....||:|:|..| .:..|...|:..
Mouse   340 ETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPS 404

  Fly   242 MLCAGLVQQGGKDACQGDSGGPLIVNEGR-YKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRK 304
            |||||.: :||.|:|||||||||:..|.| :||.|..|||.|||:.|.||||.|::.|||||.:
Mouse   405 MLCAGYL-KGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	97/234 (41%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	98/237 (41%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133	5/12 (42%)
		Tryp_SPc	238..465	CDD:214473	97/234 (41%)
		Tryp_SPc	239..468	CDD:238113	98/237 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56985
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3996
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11120
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860