DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and tmprss2.1

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_004912265.1	Gene:	tmprss2.1 / 101731874	XenbaseID:	XB-GENE-22065907	Length:	482	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	98/243 - (40%)
Similarity:	132/243 - (54%)	Gaps:	11/243 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 CFCGTPNV-NRIVGGQQVRSNKYPWTAQL-VKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQI 128
            |...|.|| ||||||.|.....:||...| ...||    .||||:|...|:|||||||.|.....
Frog   237 CGSSTKNVGNRIVGGSQASLGDWPWQVSLQFNERH----ICGGSIITPNYILTAAHCVEGVYSSP 297

  Fly   129 TIRLLQIDRSSRDPGIVRKVVQTTV-HPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANHN 192
            ....:.:....:..|..|..|::.: |.|||.....||:||::|:||:.||..::|||||.|...
Frog   298 YPWTVYVGSLYKSTGGTRYSVKSLIGHQNYDTKTKNNDIALMRLKSPITLTSTVQPVCLPNAGML 362

  Fly   193 F-DGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQC-RQTRYKDKIAEVMLCAGLVQQGGKDA 255
            : .|::...:|||...|||.:|..|....||:|.:..| |...|...:...|:|||.: :||.|:
Frog   363 WTSGQSCWTSGWGATIEGGTSSGVLNAAMVPLIDSDTCNRAVVYNGAVTATMICAGYL-RGGIDS 426

  Fly   256 CQGDSGGPLIV-NEGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWI 302
            |||||||||:. ....:.|.|..|:|.|||..|.||||..:::.|.||
Frog   427 CQGDSGGPLVTKTSSLWWLVGDTSWGTGCANMNKPGVYGNITELLPWI 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	91/231 (39%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	92/232 (40%)
tmprss2.1	XP_004912265.1	LDLa	112..143	CDD:238060
		SRCR_2	148..241	CDD:373897	1/3 (33%)
		Tryp_SPc	248..474	CDD:238113	90/230 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I3975
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050