DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3355 and tmprss3

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	292	Identity:	109/292 - (37%)
Similarity:	158/292 - (54%)	Gaps:	33/292 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PHQTLAQQFADVVDVVDPAEQSIKAVRPPKSRNQCTAKQNC-FCG-TPNVN---RIVGGQQVRSN 85
            |....|.|.:.:..:::|:|..       .|.|..|.|  | .|| .|:..   |||||......
Frog   198 PSPKFAGQTSLLQQLINPSEYC-------SSGNVITLK--CVVCGLRPSYTSSARIVGGNVSAVG 253

  Fly    86 KYPWTAQLV-KGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQI-----TIRLLQIDRSSRDPGI 144
            ::||.|.|| :|.|    .||||||..::::||||||:   |.:     .:::.|:.::|.....
Frog   254 QWPWQASLVFQGVH----LCGGSLITPQWIVTAAHCVY---DLLYPEWWRVQVGQVSQASESAQT 311

  Fly   145 VRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANHNF-DGKTAVVAGWGLIKE 208
            ...|.:...|..|..:.:.||:||::|.||....|:::|:|||....:| :||...::|||..:|
Frog   312 AVPVQKIIYHSKYRSSTMANDIALIRLASPFTFNGSIQPICLPNYREDFPEGKICWISGWGATEE 376

  Fly   209 GGVTSNYLQEVNVPVITNAQCRQTR--YKDKIAEVMLCAGLVQQGGKDACQGDSGGPLIVNEGR- 270
            ||.||..:....||:|:|..| .|:  |...|...|:|||.: :||.|.|||||||||...:..
Frog   377 GGDTSQTMDYAGVPLISNRVC-NTKYIYGGVIKPSMVCAGFL-EGGVDTCQGDSGGPLACEDSNV 439

  Fly   271 YKLAGVVSFGYGCAQKNAPGVYARVSKFLDWI 302
            :||.|..|:|.|||.:..||||.|:|.|||||
Frog   440 WKLMGTTSWGIGCALRYKPGVYTRISSFLDWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	94/236 (40%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	95/237 (40%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055	12/46 (26%)
		Tryp_SPc	244..472	CDD:238113	95/237 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56985
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48875
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910