DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3355 and tmprss6

DIOPT Version :9

Sequence 1:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_004913946.2	Gene:	tmprss6 / 100489045	XenbaseID:	XB-GENE-1011573	Length:	806	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	102/256 - (39%)
Similarity:	157/256 - (61%)	Gaps:	19/256 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 KQNCFCGTPNVN-RIVGGQQVRSNKYPWTAQL-VKGRHYPRLFCGGSLINDRYVLTAAHCV---- 121
            :.||.||...|. |:|||.|.:..::||.|.| |:|.|    .|||:|:.|:::||||||.
Frog   557 ENNCGCGIQAVGIRLVGGTQAQEGEWPWQASLQVRGEH----ICGGTLVADQWILTAAHCFTPES 617

  Fly   122 HGNRDQITIRL--LQIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTG-NMRP 183
            :.:.:..|:.|  :::.||::.. :..||::..:||.||.:....||||:.|:..||||. :::|
Frog   618 YASPEVWTVYLGKVRLSRSTQKE-LAFKVIRLVIHPFYDEDSHDYDVALVLLDHLVPLTSPHVQP 681

  Fly   184 VCLPEANHNF-DGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQCRQTRYKDKIAEVMLCAGL 247
            :|||.:.|:| .|.:..|.|||.:||.|.||:.||:|::.::....|.:. |:.:|:..|||||
Frog   682 ICLPSSTHHFPTGSSCWVTGWGSVKENGPTSDVLQKVDIQLVAQDICTEL-YRYQISPRMLCAG- 744

  Fly   248 VQQGGKDACQGDSGGPLIVN--EGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNT 306
            .:.|.|||||||||.||:..  .||:..||:||:|.||......|||:|:::.:.||...|
Frog   745 YRDGSKDACQGDSGSPLVCKTASGRWFQAGLVSWGAGCGIPRYFGVYSRITRLVQWIESIT 805

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	94/237 (40%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	95/239 (40%)
tmprss6	XP_004913946.2	SEA	77..176	CDD:396113
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060	0/2 (0%)
		Tryp_SPc	572..804	CDD:238113	95/238 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8078
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940