Protein Alignment eif4bb and eIF4B

DIOPT Version :10

• Sequence 1: XP_005166071.1
• Gene: eif4bb / 336619
• ZFINID: ZDB-GENE-030131-8563
• Length: 632
• Species: Danio rerio
• Sequence 2: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 143/505 - (28%)
• Similarity: 226/505 - (44%)
• Gaps: 141/505 - (27%)

Zfish     1 MAASAKKNKK-KGKTLTLNDFLADETGGNAPPSFPTTKATSW-----ADETDDLEGDVSTSWHTV 59
            ||::.||.|| ||..::|..||.:   .:||..  ||:.:..     .|::||..|       |:
  Fly     1 MASAGKKGKKNKGTVISLQSFLCN---SDAPVG--TTQVSKKIRNLDGDDSDDGSG-------TL 53

Zfish    60 EDTYRAPPIDRSILPTAPRAAREPNVDRSRLPRSPPYTAFLGNLPYDVSEESIRDFFRGLAISAV 124
            ...|:        |||||||.|  ..|.:.:|...|:.|::.|||:|.:|:.:.:||.|:.:.::
  Fly    54 PLVYQ--------LPTAPRANR--IFDDNSIPHKAPFIAYINNLPFDANEDDLYEFFEGINLISL 108

Zfish   125 RLPREPNNPERLKGFGYAEFDDIESLLRALSLNEENLGNRRIRVDIADQSNDKERDSGMMSGRDR 189
            |||||.....|.:||||.|.::.|.|:..|||.:.::..||||:::   ||:.::.|...|.|..
  Fly   109 RLPREDGENGRSRGFGYVELENREDLIHVLSLPDPSIKGRRIRIEL---SNENDQQSRQKSNRRF 170

Zfish   190 DRDRGRGMDSGPDKTDSDWRARPSSDQDDGPRKDDGYGDKSRDRYESDRFRDGPRRDD------- 247
            |   |.| ::|.::...:||   ...|::|  .:.||.......:..:| :..|.|||
  Fly   171 D---GFG-NNGDNRDSGNWR---RDSQNNG--SNFGYSSNFERSFNRER-KSLPDRDDVNTPGSW 225

Zfish   248 RFSGRDRYDDRDRKDRYDDRDRRDRFDDRGSRDYDRGGFDSRGGGRRGFSSGFRRDYED----RR 308
            |.|.|.:..|                                       :|..||:.|.    .|
  Fly   226 RTSARPQSID---------------------------------------TSPTRREVEQVSEKYR 251

Zfish   309 DGD-RFGDREDRRDEGREERGPPQRPKLNLKPRSIPKEE----------------EQSGSVSPQS 356
            :|. :..||..|.:..:.|.   :|||||||||::|..:                ::.|..|
  Fly   252 EGRVKIADRYSREETSKVEE---ERPKLNLKPRTLPLPDVKTIEFEKCDVDEFNLDKQGGTS--- 310

Zfish   357 NPTNTSRASSIFGAAKPVDTAAKEREVEERL----KKEQERLQRQLEE-------DKNRPSERRP 410
                   :.::||:||||||||:|.|:|:||    |:::.|.::.|.|       |||   :...
  Fly   311 -------SLNVFGSAKPVDTAARELEIEQRLALARKQDKGRREQGLNEKLAELQVDKN---DNES 365

Zfish   411 RDRDPSWRSEEPPKERQHTGSESSHPKGSRCRDDE-HSENEVFSGQESEP 459
            .....|||:.:..||    ..:.:...|.:.||:| |..|.. .||.:.|
  Fly   366 LSATVSWRTNQDYKE----SDKINKCPGEKQRDEEIHRLNHA-RGQFNRP 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eif4bb	XP_005166071.1	RRM_eIF4B	94..175	CDD:409836	30/80 (38%)
		PTZ00459	<429..532	CDD:185638	9/32 (28%)
eIF4B	NP_001015319.1	RRM_eIF4B	78..159	CDD:409836	32/83 (39%)