DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HP6 and CBX2

DIOPT Version :9

Sequence 1:NP_608842.1 Gene:HP6 / 33661 FlyBaseID:FBgn0031613 Length:106 Species:Drosophila melanogaster
Sequence 2:XP_011523684.1 Gene:CBX2 / 84733 HGNCID:1552 Length:586 Species:Homo sapiens


Alignment Length:124 Identity:24/124 - (19%)
Similarity:42/124 - (33%) Gaps:61/124 - (49%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 GKLTFLMQWKGCDEA--GLVPAEVLNVRCPQMVISF----YEERI-------------------- 75
            |||.:|::|:|....  ...|.|  |:..|:::::|    :|:.:                    
Human    25 GKLEYLVKWRGWSSKHNSWEPEE--NILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMS 87

  Fly    76 ------------------------------VFTDEGDEEDLES---DNGYETTPSPRKK 101
                                          ..:||.|:.||::   ..|.||.|.|:||
Human    88 SCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKK 146

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HP6NP_608842.1 Chromo_shadow 25..76 CDD:279701 12/94 (13%)
CBX2XP_011523684.1 Chromo 15..61 CDD:278797 11/37 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1628171at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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