Protein Alignment ine and slc6a13

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001072913.1
• Gene: slc6a13 / 780375
• XenbaseID: XB-GENE-5947897
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 241/595 - (40%)
• Similarity: 358/595 - (60%)
• Gaps: 32/595 - (5%)

  Fly   309 PQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGG 373
            |.|.|.:..:......||..|..|       |.||::|||:..|..:||||||||||:|||:|||
 Frog    16 PPTKPLMEKEPKMEDGDMMIERGQ-------WNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGG 73

  Fly   374 VFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVII 438
            .|.:||.|.||.|.||:.|:|.::||||.:|.:.|..::||||:|.|.:|.|:..|::.||.|::
 Frog    74 AFFIPYLIFLFTCGIPVFFLETALGQYTSQGGVTAWRKICPLFEGIGYSSQVIVMLLNCYYIVVL 138

  Fly   439 GYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSE-EFFENKVLQISGGL 502
            .::::|.|.||.:|:||..|.:.|||.:| :...||.:......:.|.|. ||:|.:||:||.|:
 Frog   139 AWALFYLFNSFTSELPWASCGHSWNTENC-LDFYKGNSTHNVTLNGTSSVIEFWERRVLRISDGI 202

  Fly   503 EYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLR 567
            :..|.:.|||..||:.||::.||..||.:||:.||.|||||||::::|:|::|.|:|.||..|::
 Frog   203 DNIGGLHWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIVLLIRGVSLPGALTGIQ 267

  Fly   568 FFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLV 632
            |:..|..|.|::..||::|.:|.|.|..|..|.:.:..||||||||..||.||:..:|..||.:.
 Frog   268 FYLYPDLSRLQDPQVWMDAGTQIFFSYAICLGCLTALGSYNKYNNNCYRDCVALCFLNSGTSFVA 332

  Fly   633 GIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFA 697
            |...||.||.:|.||..::.||...|||:.|:.||:|::.||::.|||..||||::.|||:|||.
 Frog   333 GFAIFSILGFMAEEQGVHISDVAESGPGLAFIAYPRAVSMMPFSPLWACFFFFMVILLGLDSQFV 397

  Fly   698 IVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAAS-VTIM 761
            .||.:||::.|.:|. |.|.....|:::|.|.:||.|.|:..:.:||:|.|||.|:|||| :.::
 Frog   398 CVESLVTAVVDMYPT-IFRKKNRRELLILGVSMISFLVGLIMLTEGGMYVFQLFDYYAASGMCLL 461

  Fly   762 FLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHN 826
            |:|..:.:.:.|.||.......|:.|.|..|:..::.|||.:.|.:..|.::.||:.|...|| |
 Frog   462 FVAIFETLCVGWVYGADNFYDKVEHMIGYRPTGIIKYCWLFVTPAVCMATFLFSLVKYTPLTY-N 525

  Fly   827 GRYTYPDWAYGIGWMFASFSLICIP---GYAVINFLRSSGDTFWERIRNTLRPNIYECKICGEHH 888
            ..|.||.|...|||:.|..|::|||   ||.    |.:...:..||.|....|
 Frog   526 KHYVYPWWGDAIGWLLALSSMVCIPLWVGYK----LSTIKGSLMERFRQLTFP------------ 574

  Fly   889 CEHDYPEQEQ 898
             :.|.|::.|
 Frog   575 -DPDLPQKTQ 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	230/543 (42%)
slc6a13	NP_001072913.1	SLC5-6-like_sbd	37..579	CDD:444915	233/568 (41%)