Protein Alignment ine and Slc6a19

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_083154.1
• Gene: Slc6a19 / 74338
• MGIID: 1921588
• Length: 634
• Species: Mus musculus
• Alignment Length: 656
• Identity: 199/656 - (30%)
• Similarity: 329/656 - (50%)
• Gaps: 112/656 - (17%)

  Fly   306 MVNPQTPPPLGVDDDDSYLD----MSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYM 366
            ||....|.| |:::....||    :..|.|..:|:   |.||.|::|.|:|:.|||||||||||:
Mouse     1 MVRLVLPNP-GLEERIPSLDELEVIEKEEAGSRPK---WDNKAQYMLTCVGFCVGLGNVWRFPYL 61

  Fly   367 CYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMS 431
            |...|||.|::|:.|:|....||||::|.::||...:|.:|....:.|..||.|:||:.|||::.
Mouse    62 CQSHGGGAFMIPFLILLVFEGIPLLYLEFAIGQRLRKGSMGVWSSIHPALKGIGIASMFVSFMVG 126

  Fly   432 TYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFF-ENKV 495
            .||:.||.:.::|||.||:..:||.:|           |..:.......:.:::.|.::| ..:.
Mouse   127 LYYNTIIAWVMWYFFNSFQEPLPWSEC-----------PLNQNQTGYVEECAKSSSVDYFWYRET 180

  Fly   496 LQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLD 560
            |.||..:...|.::|.:..||.|||.::|....:.|:::.|..|.|:|.|:|::.|.::|.:||.
Mouse   181 LNISTSISDSGSIQWWILLCLTCAWSVLYVCIIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLK 245

  Fly   561 GAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVN 625
            ||..|:.|.|.|..:||.|.|.|::|.:|.|.|..:.||.:|||:|||..:||...|:|.||.:|
Mouse   246 GATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSVIN 310

  Fly   626 MITSLLVGIFAFSTLGNLALEQ-----NTNVRDVIG----------------------------- 656
            ..||:......:|.:|..|.|:     |||:..:|.
Mouse   311 GFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTSENFEAYQQWCNATNPQAY 375

  Fly   657 ------------------DGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVV 703
                              :|.|:.|:|:.:|:.|||.:.||:|:||.||.||||:|.|..:|.||
Mouse   376 AQLKFQTCDINSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVV 440

  Fly   704 TSIQD---GFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAF 765
            ..:||   ...:|.|      |::...:|:.:.|......:..|.|:..|:|.:|.|:.::.:||
Mouse   441 VPLQDLNITPKKWPK------ELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSFAGSIPLLIIAF 499

  Fly   766 CQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLI---------NYHE 821
            |:|.|:.:.||..|.:|:::.|.|..|:.:.:..|.|:.|.::..|::...:         :..:
Mouse   500 CEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKTLMYSIWD 564

  Fly   822 PTYH----NGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIYECK 882
            |.|.    :.:..||:|.|.:....|....:.||.:|:..|:|:.                  |:
Mouse   565 PNYEEFPKSQKIPYPNWVYAVVVTVAGVPCLSIPCFAIYKFIRNC------------------CQ 611

  Fly   883 ICGEHH 888
            ...:||
Mouse   612 KSDDHH 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	186/607 (31%)
Slc6a19	NP_083154.1	SLC5-6-like_sbd	32..612	CDD:294310	188/617 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810