Protein Alignment ine and slc6a1a

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001038752.2
• Gene: slc6a1a / 692318
• ZFINID: ZDB-GENE-060519-23
• Length: 679
• Species: Danio rerio
• Alignment Length: 642
• Identity: 250/642 - (38%)
• Similarity: 383/642 - (59%)
• Gaps: 44/642 - (6%)

  Fly   278 LASIGIGSTDGRKLVIRRVPTTANELFDMVNPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWAN 342
            :|:....||||      :|.|..||:.....|:|        :|:..:.:.:..   |.::.|..
Zfish     1 MATNNTKSTDG------QVVTELNEITTNDKPKT--------EDAKPEKNKKDI---PDRETWGG 48

  Fly   343 KMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIG 407
            |..|:|:|:||::||||||||||:|.|:|||.||:||.:.|....:||.|:|.::||||.   ||
Zfish    49 KFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLECALGQYTS---IG 110

  Fly   408 ALG--QLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVP 470
            .||  :|.|:|||.|||:.|:||.::.||.|||.:::||.:.||.|::||..|||.|||..|:.
Zfish   111 GLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIIAWALYYLYNSFTTDLPWKSCNNPWNTDRCYT- 174

  Fly   471 QRKGINASAPDTSRTPSE--EFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKS 533
                 |.|..||:...|.  ||:|..|.|::.|||.||.:|..|...|..||::|||..||.:..
Zfish   175 -----NYSIVDTTNLTSAVMEFWERNVHQMTDGLEKPGEIRVPLAITLAIAWVLVYFCIWKGVSW 234

  Fly   534 SAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITF 598
            :.||.||:||:|:.::.||.:|.|||.||.||:.|:..|.:.:||.:.||::||:|.|.|.|:..
Zfish   235 TGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYITPDFEKLKESEVWLDAATQIFFSYGLGL 299

  Fly   599 GSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIF 663
            ||:|:..|||.:|||:.||::.|..:|..||:..|...||.:|.::......:.||...|||:.|
Zfish   300 GSLIALGSYNPFNNNVYRDSIIVCCINSFTSMFAGFVIFSIVGFMSHVTKRPIADVAASGPGLAF 364

  Fly   664 VVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFV 728
            :.||:|:.::|.:.|||::||.|||.||::|||..||..:|::.|.|||.:::.   .||.:..|
Zfish   365 LAYPEAVTQLPVSPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEFPRLLRKR---REIFIACV 426

  Fly   729 CVISCLFGMPNIIQGGIYYFQLMDHYAAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAP 792
            ||:|...|:.||.|||:|.|:|.|:|:|| :.::||.|.:.|:|:|.||..:...|:::|.|..|
Zfish   427 CVVSYAIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECISISWCYGVNKFYDNIQEMIGYKP 491

  Fly   793 SFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVIN 857
            ..:.:.||:...|.::..:::.|.:.....|.:|  |.:|.|..|:||:.|..|::.||||....
Zfish   492 CIWWKLCWVFFTPLVVAGVFLFSAVQMVPLTMNN--YVFPKWGQGVGWLMALSSMVLIPGYMGYM 554

  Fly   858 FLRSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQEQFMLAQEMATVYKPTNP 914
            ||...| |:.||||..|:|...:       ..:.:.|||:|.....:..:..:|.:|
Zfish   555 FLNLKG-TYKERIRIMLQPPAVK-------RAQENGPEQQQSQPPIQEQSPQQPQSP 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	230/543 (42%)
slc6a1a	NP_001038752.2	SLC5-6-like_sbd	2..588	CDD:444915	247/624 (40%)