Protein Alignment ine and slc6a4b

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001170930.1
• Gene: slc6a4b / 664770
• ZFINID: ZDB-GENE-060314-2
• Length: 591
• Species: Danio rerio
• Alignment Length: 540
• Identity: 209/540 - (38%)
• Similarity: 336/540 - (62%)
• Gaps: 10/540 - (1%)

  Fly   340 WANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRG 404
            |:.||.|:|:.||::|.|||||||||:||::|||.||:||.::.....:||.:|||::||:...|
Zfish    41 WSKKMDFLLSVIGFAVDLGNVWRFPYICYQNGGGAFLIPYVLMAVFGGVPLFYMELALGQFHRTG 105

  Fly   405 PIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWV 469
            .|.....:||:|||.|.|..:::..:|.||:.||.::::||::||.:.:||..|:|.|||.:|..
Zfish   106 AISIWKHICPIFKGIGFAICIIALYVSFYYNTIIAWALFYFYSSFSSTLPWTSCDNDWNTENCTN 170

  Fly   470 PQRKGINASAPDTSRTPSEEFFENKVLQI--SGGLEYPGMMRWELFACLICAWLMVYFATWKSIK 532
            ...|. |.:..:.||:|:|||:...||.:  |.||...|.:||:|..||...:.:|||:.||.:|
Zfish   171 YFGKD-NVTWTNYSRSPAEEFYTRNVLAVHESSGLGNVGYIRWQLMLCLFLIFTIVYFSLWKGVK 234

  Fly   533 SSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGIT 597
            :|.||.:.|||.|:|:::|||:|..||.||.:|:.|:..|||.:||..:||::||:|.|.|||..
Zfish   235 TSGKVVWVTATLPYVVLLILMIRGATLPGAWKGVVFYLNPKWEKLKETSVWVDAAAQIFFSLGPG 299

  Fly   598 FGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGD-GPGM 661
            ||.:::.:|||.:.||..||.:..|.||.:||.:.|...|:.||.:|.::|.||.||..| ||.:
Zfish   300 FGVLLALSSYNPFTNNCYRDAIVTSLVNCLTSFVSGFVIFTVLGYMAEQRNVNVEDVARDKGPSL 364

  Fly   662 IFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVL 726
            :|:.||:|:|.|..:..:|::||.|::.|||:|.|..:|.::|::.|.:|..:...   .|:.||
Zfish   365 LFITYPEAIANMVGSTFFAIIFFVMMITLGLDSTFGGLEAIITAVMDEYPDVLSHR---RELFVL 426

  Fly   727 FVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKA 791
            .:.|:..|..:..:.:||.|..:|::.:....:|:.:.|.:..|::||||..|.|.::|.|.|..
Zfish   427 GLVVVCFLGSLSTLTKGGAYVVKLLEEFGVGSSIIAIVFLEATAVSWFYGINRFSNDIKSMLGYT 491

  Fly   792 PSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVI 856
            |..:.:.||:.:.|..|..|.:.||:|....|..:  |.:|||:..:|::..:.|.|.||.|.|.
Zfish   492 PGLFWKVCWVAISPAFLAYIIISSLLNPQTLTLFD--YEFPDWSITVGYIIGASSFIWIPIYMVY 554

  Fly   857 NFLRSSGDTFWERIRNTLRP 876
            ..:.:.| :..:|:...|||
Zfish   555 KLVWTPG-SLKQRLAVCLRP 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	207/538 (38%)
slc6a4b	NP_001170930.1	SLC6sbd_SERT	38..574	CDD:271399	209/540 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820