Protein Alignment ine and SLC6A13

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Alignment Length: 573
• Identity: 235/573 - (41%)
• Similarity: 362/573 - (63%)
• Gaps: 17/573 - (2%)

  Fly   308 NPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGG 372
            |.:|.|...|      ::..:|...|:  :.||.|||:|||:..|..:||||||||||:|||:||
Human    11 NGETKPVYPV------MEKKEEDGTLE--RGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGG 67

  Fly   373 GVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVI 437
            |.|.:||.:.||.|.||:..:|.::||||.:|.:.|..::||:|:|.|.||.::..|::.||.::
Human    68 GAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIV 132

  Fly   438 IGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSR---TPSEEFFENKVLQIS 499
            :.::::|.|:||..::||..|.:.|||..|...|:  .|.|...||.   :|..||:|.:||:||
Human   133 LAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQK--TNGSLNGTSENATSPVIEFWERRVLKIS 195

  Fly   500 GGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAE 564
            .|:::.|.:||||..||:.||::.||..||.:||:.||.|||||||::::::|::|.|||.|||:
Human   196 DGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQ 260

  Fly   565 GLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITS 629
            |::|:..|..:.|.:..||::|.:|.|.|..|..|.:.:..|||||:||..||.:|:..:|..||
Human   261 GIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTS 325

  Fly   630 LLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNS 694
            .:.|...||.||.::.||...:.:|...|||:.|:.||:|:..:|::.|||..||||::.|||:|
Human   326 FVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDS 390

  Fly   695 QFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAAS-V 758
            ||..||.:||::.|.:|. :.|.....|:::|.|.|:|.|.|:..:.:||:|.|||.|:|||| :
Human   391 QFVCVESLVTALVDMYPH-VFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGM 454

  Fly   759 TIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPT 823
            .::|:|..:.:.:||.||..|...|::.|.|..|...::.|||.|.|.:..|.::.|||.|...|
Human   455 CLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLT 519

  Fly   824 YHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRP 876
            | |.:||||.|...:||:.|..|::|||.:::.......| .|.||||..:.|
Human   520 Y-NKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKG-PFRERIRQLMCP 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	228/542 (42%)
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		4/16 (25%)
		SLC6sbd_GAT2	32..575	CDD:271396	229/544 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2921
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770