Protein Alignment ine and si:ch211-132b12.2

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001038688.1
• Gene: si:ch211-132b12.2 / 571877
• ZFINID: ZDB-GENE-050420-178
• Length: 582
• Species: Danio rerio
• Alignment Length: 579
• Identity: 223/579 - (38%)
• Similarity: 344/579 - (59%)
• Gaps: 12/579 - (2%)

  Fly   326 MSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPL 390
            |.....|::.| .:|.:|.:|:||..|..:||||||||||:|||:|||.|||||.:.:..|.:||
Zfish     1 MGKVKGQIEER-GNWGSKTEFILAVAGIVIGLGNVWRFPYLCYKNGGGAFLVPYLVFVVTCGVPL 64

  Fly   391 LFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPW 455
            ..:|.::||||..|.|....:||||.:|.|.|..::......||.:|:.::::|...||.:::||
Zfish    65 FLLETAMGQYTQEGGITCWHRLCPLAEGIGYAGQLIVLYSCMYYIIILAWALFYLAFSFSSQLPW 129

  Fly   456 IDCNNRWNTPDCWVPQRKGINASAPDTSRTPSE--EFFENKVLQISGGLEYPGMMRWELFACLIC 518
            ..|:|.|||..|.......:|.|.|....:.|.  ||::::||.:|||:|..|.:.||:..|||.
Zfish   130 ASCDNIWNTDACVNLAENKLNLSTPMLLNSTSSVTEFWQHRVLALSGGIEKVGKINWEILLCLIV 194

  Fly   519 AWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVW 583
            .|::.||..||.:||:.||.|||||||:|::::|::|.:||.||.:|:.|:..|:.:.|.:..||
Zfish   195 MWIICYFCVWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLYPEPARLADPQVW 259

  Fly   584 INAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQN 648
            :.|.:|.|.|..:...|:....||||||.|..|.::.:..:|..||::.|...||.||.:|.:|.
Zfish   260 MEAGAQIFFSYALGTASLTVLGSYNKYNYNCYRSSLWLCLLNSSTSVIAGFAVFSVLGFMAQKQG 324

  Fly   649 TNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRW 713
            ..:.:|...|||:.|:.||||:|.||:.||||..||.|::.|||::||..:||.:||:.|.||.
Zfish   325 LPIEEVAESGPGLAFIAYPQAVAMMPFPQLWAACFFIMIILLGLDTQFVAMEVFMTSVIDLFPT- 388

  Fly   714 IKRHLGYHEIVVLFVCVISCLFG-MPNIIQGGIYYFQLMDHYAAS-VTIMFLAFCQMIAIAWFYG 776
            :.|..|..||.:|..|:. |.|| :..:.:||:|.|||.|:||.| ..::||...:.:|:.|.:|
Zfish   389 VLRKAGRREIFLLLFCLF-CFFGQLVMVTEGGMYVFQLFDYYACSGACLLFLCVFESLAMGWVFG 452

  Fly   777 TGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWM 841
            ..::...::.||...|:::...||..|.|.:..|.:|.||:.| :|...|..|.||||||.:||:
Zfish   453 AEKMFGIIEDMTNSRPNYWFMLCWKYLTPIVSLASFVCSLVKY-KPLTFNRWYVYPDWAYVLGWL 516

  Fly   842 FASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNI---YECKICGEHHCEHDYPEQE 897
            .|..|::.:||:|:.......| :..:|..:...|:.   :.|||..:.|.:....|.|
Zfish   517 LALSSILLVPGWALGRMFAGKG-SIKQRWSHLCSPDTNPHFACKIQNKRHEKTPVTEME 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	213/542 (39%)
si:ch211-132b12.2	NP_001038688.1	SLC6sbd-TauT-like	11..550	CDD:271387	214/543 (39%)