Protein Alignment ine and slc6a6b

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_073792781.1
• Gene: slc6a6b / 569098
• ZFINID: ZDB-GENE-030131-3077
• Length: 629
• Species: Danio rerio
• Alignment Length: 614
• Identity: 256/614 - (41%)
• Similarity: 373/614 - (60%)
• Gaps: 34/614 - (5%)

  Fly   328 DETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLF 392
            ||.....|:::.||:|:.|:|:..|..|||||||||||:|||:|||.||:||.|.||...:|:.|
Zfish    36 DEAEGKHPQREKWASKLDFLLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFF 100

  Fly   393 MELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWID 457
            :|:::||:|..|.|....:|||:|.|.|.||:|:..|::.||.||:.:.:||.|..|:.|:||..
Zfish   101 LEVALGQFTSEGGITCWEKLCPIFTGIGYASIVIVSLLNIYYIVILAWGLYYLFQCFQPELPWAS 165

  Fly   458 CNNRWNTPDC---WVPQRKGINASAPDTSRT-PSEEFFENKVLQISGGLEYPGMMRWELFACLIC 518
            |||:|||.:|   .:.:.|.:.|:|..|:.| |..||:|..||.||.|:|..|.::|:|..||:.
Zfish   166 CNNKWNTENCVEDTLRRNKTLWAAANATNFTSPVTEFWERNVLSISDGIEEVGHVKWDLALCLLA 230

  Fly   519 AWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVW 583
            .|::.:|..||.:||:.||.|.|||||||::|:|:||.|||.|||||::|:..|..:.|.:..||
Zfish   231 MWVICFFCIWKGVKSTGKVVYVTATFPFVMLIVLLVRGVTLPGAAEGIKFYLYPNVTRLGDPEVW 295

  Fly   584 INAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQN 648
            |:|.:|.|.|..|..|:|.|..|||||..|..||.:.:..:|..||.:.|...||.||.:|.||.
Zfish   296 IDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCLLLGGLNSATSFVSGFAIFSVLGFMAQEQG 360

  Fly   649 TNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRW 713
            .::.||...|||:.|:.||:|:..||....||::||.|||.|||:|||..||..:||:.|.:|.:
Zfish   361 VDIADVAESGPGLAFIAYPKAVTMMPLPTFWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSF 425

  Fly   714 IKRHLGY-HEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAAS-VTIMFLAFCQMIAIAWFYG 776
            :::  || .||.:..||.:|.|.|:..:.:||:|.|||.|:|||| |.::::||.:.||:||.||
Zfish   426 LRK--GYRREIFIAIVCFVSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECIAVAWVYG 488

  Fly   777 TGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWM 841
            .......:::|.|..|:.:::..|.|:.|.|....::.||:.| .|..:|..|.||||:.|:||.
Zfish   489 ADNFYDAIEEMIGYRPNPWMKWSWTVVTPFLCVGCFIFSLVKY-APLRYNKIYEYPDWSIGVGWT 552

  Fly   842 FASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIYECKICGEHHCEHDY-PEQEQFMLAQEM 905
            .|..|:||||...||..::|.|... |||:....|     ...|...|..:| |:..:  |||
Zfish   553 LALASMICIPMVVVIKIIQSDGPLI-ERIKAVAAP-----VRGGASSCPQEYQPKSNE--LAQ-- 607

  Fly   906 ATVYKPTNPHLLNLGQKCGYNAMQASPSH 934
                 |.:|:         :|...|.|:|
Zfish   608 -----PLDPN---------WNGGLAKPTH 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	239/544 (44%)
slc6a6b	XP_073792781.1	None