DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ine and si:ch211-283g2.1

DIOPT Version :9

Sequence 1:	NP_001162871.1	Gene:	ine / 33659	FlyBaseID:	FBgn0011603	Length:	943	Species:	Drosophila melanogaster
Sequence 2:	XP_017211707.1	Gene:	si:ch211-283g2.1 / 569007	ZFINID:	ZDB-GENE-060531-57	Length:	581	Species:	Danio rerio

Alignment Length:	559	Identity:	271/559 - (48%)
Similarity:	384/559 - (68%)	Gaps:	18/559 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 WANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRG 404
            |:.:::|.||.||.:|||||:|||||:||:||||.||:||.::|.:..||||.|||::|||..||
Zfish    12 WSRQIEFTLAGIGCAVGLGNIWRFPYLCYRSGGGAFLLPYLLMLVVLGIPLLHMELTLGQYLRRG 76

  Fly   405 PIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWV 469
            |:.||.:.||||||.|:|:|.:||:|.|||::||.:::||.|:||::|:.|.:|||.|||.:|
Zfish    77 PVLALAKACPLFKGVGMATVAISFIMCTYYNIIITWALYYMFSSFRSELLWQNCNNTWNTVNC-- 139

  Fly   470 PQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSS 534
             ..:..|:|   :|.|.|::||..|||:.:.|:|..|.:|||||..|:.||::||...:|.:||:
Zfish   140 -TDQVTNSS---SSSTASQQFFNYKVLERTSGVEETGTLRWELFLLLLLAWILVYLCIFKGVKST 200

  Fly   535 AKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFG 599
            .||.||||.||:|:::.|::..|.|.||.:|::||..|:|.:|.|..||||||:|.|||:||.||
Zfish   201 GKVVYFTALFPYVILLALLINNVQLPGALDGIKFFIIPEWDKLLNVQVWINAAAQIFNSIGIGFG 265

  Fly   600 SMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFV 664
            |:::.||||.||||:|:||:|::..|.:||:..|...||..|.::..||..|.::..||||::.|
Zfish   266 SLMAMASYNNYNNNVLKDTLAIAITNSLTSIFAGFVIFSAFGYMSHLQNVPVSEIAVDGPGLVLV 330

  Fly   665 VYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVC 729
            |||||...||.|.|||.:||||||||||:||||:|||:|||:.|.:.:.|.:||...|.:||.||
Zfish   331 VYPQAFVTMPVAPLWAFLFFFMLLCLGLDSQFAMVEVMVTSLLDSYSKPILKHLKRKEFLVLLVC 395

  Fly   730 VISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSF 794
            ..:.|.|:||::|.|||.|||||||.|.|:||||||.:::.:.|.||..|||.|:.:||||.||.
Zfish   396 GAAFLLGIPNVMQVGIYVFQLMDHYTAIVSIMFLAFFEVVGVCWCYGVKRLSSNLVEMTGKRPSI 460

  Fly   795 YLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFL 859
            :.|.||.|:.|.|:..|.|.|:|.:....|.:  |.||.||.|:||:.|..|:|.|| .|.::.|
Zfish   461 FFRICWWVICPALITVILVFSVIQFKPARYED--YVYPPWAQGVGWLIALASIIWIP-LAAVHTL 522

  Fly   860 RSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQEQ 898
            .....:|.|:.:.::.|...:         |.|.|..:|
Zfish   523 WVLPGSFTEKFKKSITPFSLD---------EDDSPYYQQ 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	266/535 (50%)
si:ch211-283g2.1	XP_017211707.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	559	1.000	Domainoid score	I236
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76482
Inparanoid	1	1.050	562	1.000	Inparanoid score	I1051
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0013222
OrthoInspector	1	1.000	-	-		otm25739
orthoMCL	1	0.900	-	-		OOG6_109184
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17278
SonicParanoid	1	1.000	-	-		X8703
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	13.000