Protein Alignment ine and slc6a15

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001232001.1
• Gene: slc6a15 / 565315
• ZFINID: ZDB-GENE-050420-93
• Length: 741
• Species: Danio rerio
• Alignment Length: 674
• Identity: 210/674 - (31%)
• Similarity: 326/674 - (48%)
• Gaps: 127/674 - (18%)

  Fly   271 DVT-SVRSLASIGIGSTDGRK---LVIRRVPTTANELFDMVNPQTPPPLGVDDDDSYLDMSDETA 331
            ||| ||:.|.|......|..|   |::..||.         |.|.....|.::::      :|..
Zfish    16 DVTESVKDLLSNEDSCDDSFKKSSLMVGDVPQ---------NKQKDVEEGSEEEE------EEEE 65

  Fly   332 QLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELS 396
            :.:|.   |.:|:|::||.:|:||||||||||||:|.|:|||.:||||.|:|.:..|||.|:||:
Zfish    66 EERPA---WGSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPLFFLELA 127

  Fly   397 VGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDC--- 458
            |||...||.||....:.|...|.|.||.:|.|.::.||:||||:|::||..||:..:||.:|
Zfish   128 VGQRIRRGSIGVWNYISPHLGGIGFASCLVCFFVALYYNVIIGWSLFYFSQSFQQPLPWHECPLV 192

  Fly   459 NNRWNT---PDCWVPQRKGINASAPDTSRTPSEEFFENKV-LQISGGLEYPGMMRWELFACLICA 519
            .|:.||   |:|               .::.:..::..:| |.||..:...|.:.|.:..||:.|
Zfish   193 KNKTNTYIEPEC---------------EKSSATTYYWYRVALDISDSISEGGGLNWRMTLCLLAA 242

  Fly   520 WLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWI 584
            |.||..|..|.|:||.||.||::.||:|::|..:.||..|.|:.:|:...|.||...:....||.
Zfish   243 WTMVCLAMIKGIQSSGKVMYFSSLFPYVVLICFLARAFLLKGSVDGIIHMFTPKLEIMLEPKVWR 307

  Fly   585 NAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNT 649
            .||:|.|.:||:.||.:|:|:||||.:||...|.|.||.:|..||:|..:..|:.||..|...|.
Zfish   308 EAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIMNA 372

  Fly   650 -----NVRDVIG----------------------------------------------------- 656
                 |.:.:||
Zfish   373 KCVEMNTKKIIGFLGKEINPGLIPHHINFSQVSPEDYQQMTNIIQGVMENDYPRLGLDNCDIKEE 437

  Fly   657 -----DGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKR 716
                 .|.|:.|:.:.:||...|.:..|:||||.||:.|||.|.|..::.::|.|.|.|.  :::
Zfish   438 LNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIQGILTPIVDTFK--VRK 500

  Fly   717 HLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLS 781
                 |.:.:..||::...|:..:.:.|.|:..:.|.|:|::.::.:...:.||:||.|||.:..
Zfish   501 -----EYLTVGCCVLAFFIGLTFVQRSGNYFVAMFDDYSATLPLLIVVLLENIAVAWVYGTDKFF 560

  Fly   782 KNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLI--NYHEPTY--------HNGRYTYPDWAY 836
            :::|.|.|..|..|....|..:.|.||..:...|:|  ....|:|        .....:||.|..
Zfish   561 EDLKDMLGFTPYRYYYYMWKFVTPVLLLGLLAASVIQLGLAPPSYSAWNQQLAKEQSLSYPPWGL 625

  Fly   837 GIGWMFASFSLICIPGYAVINFLR 860
            .:.......:::.:|   |:..||
Zfish   626 AVCISLVVTAILPVP---VVFILR 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	193/604 (32%)
slc6a15	NP_001232001.1	SLC5-6-like_sbd	68..646	CDD:444915	192/605 (32%)