Protein Alignment ine and slc6a1b

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001007363.1
• Gene: slc6a1b / 492490
• ZFINID: ZDB-GENE-041114-57
• Length: 600
• Species: Danio rerio
• Alignment Length: 642
• Identity: 247/642 - (38%)
• Similarity: 379/642 - (59%)
• Gaps: 56/642 - (8%)

  Fly   278 LASIGIGSTDGRKLVIRRVPTTANELFDMVNPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWAN 342
            :|:.|..::||..|.......|||:     .|:|            |.:..:..:..|.::.|..
Zfish     1 MATNGTKASDGHVLTEVNEAPTAND-----KPKT------------LVVKVQKKKELPDRETWQG 48

  Fly   343 KMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIG 407
            |..|:|:|:||::||||||||||:|.|:|||.||:||.:.|....:||.|:|.::||||.   ||
Zfish    49 KFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLETALGQYTS---IG 110

  Fly   408 ALG--QLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVP 470
            .||  :|.|:|||.|||:.|:||.::.||.|||.::|||.:.||.|::||..|:|.|||..|:
Zfish   111 GLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIIAWAIYYLYNSFTTDLPWKSCDNPWNTDKCF-- 173

  Fly   471 QRKGINASAPDTSRTPSE--EFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKS 533
                .|.|..:.....|.  ||:|..:.|::.|||.||.:|..|...|..||::|||..||.:..
Zfish   174 ----SNYSMANIGNMTSAVVEFWERNMHQLTDGLEKPGEIRLPLAITLAIAWVLVYFCIWKGVGW 234

  Fly   534 SAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITF 598
            :.||.||:||:|:.::.||.:|.|||.||.||:.|:..|::|:||.:.||::||:|.|.|.|:..
Zfish   235 TGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYVTPEFSKLKESEVWLDAATQIFFSYGLGL 299

  Fly   599 GSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIF 663
            ||:|:..|||.:|||:.:|::.|..:|..||:..|...||.:|.:|......:.||...|||:.|
Zfish   300 GSLIALGSYNPFNNNVYKDSIIVCCINSFTSMFAGFVIFSIVGFMAHITKRPIADVAASGPGLAF 364

  Fly   664 VVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFV 728
            :.||:|:.::|.:.||||:||.|||.||::|||..||..:|::.|.|||.::   |..||.:..|
Zfish   365 LAYPEAVTQLPISPLWAVLFFSMLLMLGIDSQFCTVEGFITALVDEFPRALR---GRREIFIAVV 426

  Fly   729 CVISCLFGMPNIIQGGIYYFQLMDHYAAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAP 792
            |::|.|.|:.||.|||:|.|:|.|:|:|| :.::||.|.:.::|:||||..:...|:::|.|..|
Zfish   427 CLVSYLIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFECVSISWFYGVNKFYGNLEEMIGYKP 491

  Fly   793 SFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVIN 857
            ..:.:.||:|..|.::..:::.|.:.....|.:|  |.:|.|..|:||..|..|::.||||....
Zfish   492 CIWWKLCWVVFTPLIVAGVFLFSAVQMVPLTLNN--YVFPKWGQGVGWCMALSSMVLIPGYMGYM 554

  Fly   858 FLRSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQEQFMLAQEMATVYKPTNP 914
            ||...| ::.||:|..::|.....:      .:.:.|||:             |.||
Zfish   555 FLTLKG-SYKERLRIMIQPTAAAVR------TQENGPEQQ-------------PENP 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	228/543 (42%)
slc6a1b	NP_001007363.1	SLC5-6-like_sbd	2..600	CDD:444915	247/641 (39%)