DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ine and Gat

DIOPT Version :9

Sequence 1:	NP_001162871.1	Gene:	ine / 33659	FlyBaseID:	FBgn0011603	Length:	943	Species:	Drosophila melanogaster
Sequence 2:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	579	Identity:	229/579 - (39%)
Similarity:	355/579 - (61%)	Gaps:	38/579 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 DMSDETAQLK----PRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFI 385
            |.|::...:|    |.:..|::||.|:|:.:|.::||||||||||:|||:|||.|::||.|.||:
  Fly    42 DTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFL 106

  Fly   386 CSIPLLFMELSVGQYTGRGPIGALG--QLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTS 448
            ..||:.||||::||..   .||.||  ::.|:|||.|.|:.|:|..|:.||.||:.::::|||.|
  Fly   107 AGIPMFFMELALGQML---TIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMS 168

  Fly   449 FKTEMPWIDCNNRWNTPD-----------CW----------VPQRKGINASAPDTSRTPSEEFFE 492
            .:.::||..|||.|||.:           ||          |.....:|.::.:.: .|.:||:|
  Fly   169 MRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELT-DPVKEFWE 232

  Fly   493 NKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAV 557
            .:.||||.|:|..|.:||||...|:..|::.||..||.:|.:.||.||||.||:||:.||:||.:
  Fly   233 RRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGI 297

  Fly   558 TLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVS 622
            ||.||.||::|:..|.:|:|.|:.|||:|.:|.|.|.|:..|::::..||||:.||:.:|.:.|.
  Fly   298 TLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVC 362

  Fly   623 AVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFML 687
            .||..||:..|...||.:|.:|.||...|.||...|||:.|:|||.|:.::|.:.:|:.:|||||
  Fly   363 TVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFML 427

  Fly   688 LCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMD 752
            |.:||:|||..:|..:|:|.|.:|:.:::.   .||.:..||.:|.|.|:..|.|||:|.||::|
  Fly   428 LLIGLDSQFCTMEGFITAIIDEWPQLLRKR---KEIFIAIVCALSYLVGLTCITQGGMYIFQILD 489

  Fly   753 HYAAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSL 816
            .||.| ..:::|.|.:.::|:|.||..|....:|.|.|..|:.:.:.||.|..|.:...::..::
  Fly   490 SYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNI 554

  Fly   817 INYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLR 875
            :.:....|.:  |:||.||:..||..|..|::.||.|....:.|:.|: ..|:||..:|
  Fly   555 VQWTPVKYLD--YSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGE-LSEKIRALVR 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	225/563 (40%)
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	225/563 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440724
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850