Protein Alignment ine and Slc6a16

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001311464.1
• Gene: Slc6a16 / 381884
• MGIID: 2685930
• Length: 742
• Species: Mus musculus
• Alignment Length: 652
• Identity: 167/652 - (25%)
• Similarity: 270/652 - (41%)
• Gaps: 143/652 - (21%)

  Fly   296 VPTTANELFDMVNPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNV 360
            |.|...|..::||                .||.|:::..|.:|.||:|::::||.:.|.:....|
Mouse   100 VTTLEQESSELVN----------------RMSRESSEGYPPRQLWASKVEYMLAIMSYLLMPSGV 148

  Fly   361 WRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVV 425
            .||.......|...|.:.|.::|....|||||:|::|||...:........|.|.|.|.|.:.|:
Mouse   149 LRFASGWVHKGSCSFFIAYILMLLGIGIPLLFLEMAVGQRAQQSSADMWKNLSPWFGGVGYSMVM 213

  Fly   426 VSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNT----PDCWVPQRKGINASAPDTSRTP 486
            |.|:.:||.:|...:.::|....|...:||..|..:.|:    |:|              ...|.
Mouse   214 VCFITNTYLNVFNSWILFYMSHIFYFVVPWDQCPLQRNSSNFDPEC--------------EQATS 264

  Fly   487 SEEFFENKVLQISGGLEYPGM------MRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFP 545
            ...|:..|.|:.|..:|..|.      |...|..|||||:|:      ..|||..||.:.....|
Mouse   265 YTYFWYRKTLKASDRIEDGGQPSFSLGMSLFLSFCLICAFLV------NGIKSIGKVLFVLLLVP 323

  Fly   546 FVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKY 610
            :.:|:..::|.:::|||..||:.....|.:.:.:..:|.:|..|....:|:.||.::|.||:...
Mouse   324 YSIIVCFLIRTLSMDGAEYGLKHLLILKVASISDLTIWCHAGIQVLFDIGLGFGPIVSLASHVPD 388

  Fly   611 NNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLAL---------EQNTNVRDV------------ 654
            .||.:.|...::...:||.|:...|..|.||..|.         .|.|.:|.|
Mouse   389 FNNCMADAFLMALFKIITLLMTTPFLLSILGFWATTTTHHCCKKNQETLLRLVAQGILPPDAQPP 453

  Fly   655 ----------------------------------------IGDGPGMIFVVYPQAMAKMPYAQLW 679
                                                    |.|.|..:|:::.:.::.:|.:..|
Mouse   454 DLSGNPTSNYNSWLSSLPPPLRSAVLSVVPECSVQKQFLKIKDNPRFLFLIFTEVISLLPGSGFW 518

  Fly   680 AVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLF--GMPNIIQ 742
            .|:||.:||.|||.|....:...|.::||.|| :.:|     :..:|.|||...:|  |:..|..
Mouse   519 IVLFFLLLLTLGLCSNLMFMLGNVLTLQDTFP-FCRR-----QPRLLIVCVSMAMFLCGLIFIQP 577

  Fly   743 GGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSF--------YLRS- 798
            .|||||.|:.....:|.::.:..|:.:|:||.||..|...::..:.|: |.|        |:..
Mouse   578 SGIYYFSLLSECWVAVPVIIIIICENLAVAWAYGADRFLADMVALLGR-PIFSGCGWLWCYISPM 641

  Fly   799 ----------CWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGY 853
                      .:||.||.:.|| |..|       |.......:|:|:..:......|.|:.||.|
Mouse   642 VVLGLLTSVFVYLVKGPLVYFA-WDSS-------TSKEVVRVFPEWSKILIAGLTVFVLMPIPAY 698

  Fly   854 AV 855
            .|
Mouse   699 FV 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	158/611 (26%)
Slc6a16	NP_001311464.1	SLC5-6-like_sbd	125..694	CDD:294310	154/603 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920