Protein Alignment ine and SerT

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 244/693 - (35%)
• Similarity: 383/693 - (55%)
• Gaps: 75/693 - (10%)

  Fly   282 GIGSTDGRKLVIRRVPTTANELFDMVNPQTPPPLGVD------DDDSYLDMSDETAQLK------ 334
            |..:|.||                    ..|.|...|      :|||..|..|.|...|
  Fly    11 GAAATTGR--------------------SNPAPWSDDKESPNNEDDSNEDDGDHTTPAKVTDPLA 55

  Fly   335 PR----------------QQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIIL 383
            |:                ::.|..|.:|:||.||::|.|||||||||:||::|||.||||||:.|
  Fly    56 PKLANNERILVVSVTERTRETWGQKAEFLLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFL 120

  Fly   384 FICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTS 448
            ....:||.:|||::||:...|.:....::||..||.|.|..::...|..||:.|||:::||.|.|
  Fly   121 IFGGLPLFYMELALGQFHRCGCLSIWKRICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFAS 185

  Fly   449 FKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQI--SGGLEYPGMMRWE 511
            |.:::||..|:|.|||.:|    .:..:.:..:.:.:|::||||.|||:.  ..||::.|.::..
  Fly   186 FTSKLPWTSCDNPWNTENC----MQVTSENFTELATSPAKEFFERKVLESYKGNGLDFMGPVKPT 246

  Fly   512 LFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSE 576
            |..|:...:::|||:.||.::|:.||.:.||..|:|::|||:||.|:|.||.||::::..|:|.:
  Fly   247 LALCVFGVFVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHK 311

  Fly   577 LKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLG 641
            |||:.|||:||||.|.|||..||::::.:||||:|||..||.:..|::|.:||.|.|...||.||
  Fly   312 LKNSKVWIDAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLG 376

  Fly   642 NLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSI 706
            .:|..|.|::..|..:|||::|:|||:|:|.|..:..|:::||.||:.|||:|.|..:|.::|::
  Fly   377 YMAYVQKTSIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITAL 441

  Fly   707 QDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAI 771
            .|.:||.|.|.   .|:.||.:.....|..:|.:..||:.....::.|...:.|:|:.|.:...:
  Fly   442 CDEYPRVIGRR---RELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYGPGLAILFVVFVEAAGV 503

  Fly   772 AWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAY 836
            .||||..|.|.:|:||.|..|..:.|.||..:.|..|..|::.|::.|.|..  ...|.||||:|
  Fly   504 FWFYGVDRFSSDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEML--GEEYYYPDWSY 566

  Fly   837 GIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQEQFML 901
            .:||.....|::|||.|.:..|..:|.....:|::.:.:|         |.:|....|.|:...:
  Fly   567 QVGWAVTCSSVLCIPMYIIYKFFFASKGGCRQRLQESFQP---------EDNCGSVVPGQQGTSV 622

  Fly   902 AQEMATVY-----KPTNPHLLNLGQKCGYNAMQASPSHAEAGG 939
            ..:.|.|:     ..|:..:.||  .|..|:...||:.:.|.|
  Fly   623 XHDHAQVHVNIRTSCTSIKIYNL--NCSSNSNSLSPTTSGAEG 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	213/540 (39%)
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	214/550 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440809
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16523at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850