DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ine and GlyT

DIOPT Version :9

Sequence 1:	NP_001162871.1	Gene:	ine / 33659	FlyBaseID:	FBgn0011603	Length:	943	Species:	Drosophila melanogaster
Sequence 2:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	223/567 - (39%)
Similarity:	334/567 - (58%)	Gaps:	37/567 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 WANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRG 404
            |..:..|:|:.:||||||||||||||:||.:|||.||:|:.|:|.|..:||:|||||.|||...|
  Fly    60 WTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALG 124

  Fly   405 PIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCW- 468
            |:....:.||||:|.|...::||.::..||::||.::|:|.|.||...:||.:|...|:|..|:
  Fly   125 PVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFS 189

  Fly   469 ---VPQRKGIN-----------ASAPDTS----------RTPSEEFFENKVLQISGGLEYPGMMR 509
               ..|.:..|           .||.:.:          |.|:||:|.|.||.:|.|:|..|.::
  Fly   190 YAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSKGIEETGSIK 254

  Fly   510 WELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKW 574
            ..|.|||..||.:|:....|.::||.||.||||.||:|:::||.||.|||.||:.|:.|:..|.|
  Fly   255 LSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLTPDW 319

  Fly   575 SELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFST 639
            .:|.||.||.:||.|.|.:|...:|.:|:.:||||::||..:|::.|:..|:.||...|:..||.
  Fly   320 KQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVIFSI 384

  Fly   640 LGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVT 704
            :|.||.|.|.:|..|:..|.|:.|:|||:.:.::|.:.:|||:||.|||.|||:||||::|.|.|
  Fly   385 IGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTT 449

  Fly   705 SIQDGFPRWIKRHLGYHEI-VVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQM 768
            :|.|.||     :|..::| |||.|.:...:.|:......|:|:.||||.|||:.:::.:|..:.
  Fly   450 AILDRFP-----NLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISEC 509

  Fly   769 IAIAWFYGTGRLSKNVKQMTGKAP---SFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYT 830
            |.|||.||:.|...:::.|.||..   :|:....|..:.|..|..|...:.:.|....|  |.|.
  Fly   510 ILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKY--GHYV 572

  Fly   831 YPDWAYGIGWMFASFSLICIPGYAVINFLRSSGD-TFWERIRNTLRP 876
            ||.||..:||:.....::.|...|.....|:... :|.:||::.|:|
  Fly   573 YPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQP 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	222/565 (39%)
GlyT	NP_611836.2	SNF	57..603	CDD:249680	217/549 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16523at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920