Protein Alignment ine and slc6a22.1

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_005166076.1
• Gene: slc6a22.1 / 368923
• ZFINID: ZDB-GENE-030616-629
• Length: 584
• Species: Danio rerio
• Alignment Length: 560
• Identity: 225/560 - (40%)
• Similarity: 342/560 - (61%)
• Gaps: 9/560 - (1%)

  Fly   322 SYLD-MSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFI 385
            :|.| .|:||......:..|::|::|:||..|..:||||||||||:|||:|||||.:||.:.||.
Zfish    14 AYSDAQSNETGLKTQIRGQWSSKVEFILAVAGQIIGLGNVWRFPYLCYKNGGGVFFIPYVVFLFA 78

  Fly   386 CSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFK 450
            |.|||..||.::||||.:|.:....::||||:|.|..|.||....|.||.:|:.::.:|.|:||.
Zfish    79 CGIPLFLMETALGQYTSQGSVTCWRKICPLFEGLGYGSQVVVLYSSAYYIIILAWAFFYLFSSFS 143

  Fly   451 TEMPWIDCNNRWNTPDCWVPQR-KGI-NASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELF 513
            .|:||..|.|.||:.:|....| :|. |.|....:.:|.:||:|.:||.|:|.:...|.:||||.
Zfish   144 GELPWASCRNWWNSENCVEFDRMQGAKNLSFMANASSPVKEFWERRVLNITGSVNELGSVRWELA 208

  Fly   514 ACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELK 578
            .||:.||::.||..||.:||:.||.|||||||:|::::|::|.:||.||.:|:.|:..|..:.|.
Zfish   209 LCLLLAWVICYFCVWKGVKSTGKVVYFTATFPYVMLMVLLIRGLTLPGAIDGITFYLYPNPARLA 273

  Fly   579 NANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNL 643
            :..||::|.:|.|.|..:..|.:.:..||||||||..:|.|.:..:|..||.:.|...||.||.:
Zfish   274 DPQVWMDAGTQIFYSYALCIGCLTALGSYNKYNNNCYKDCVYLCLLNSGTSFVAGFAIFSVLGFM 338

  Fly   644 ALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQD 708
            ||||..::..|...|||:.|:.||:|:|.||.||||::.||.|::.|||:|:|..:|.::|:|.|
Zfish   339 ALEQGVDISVVAESGPGLAFIAYPRAVAMMPMAQLWSICFFLMIILLGLDSEFVGLESLMTAITD 403

  Fly   709 GFPR-WIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAAS-VTIMFLAFCQMIAI 771
            ..|. :::.|  ..::.:|.:|:...|.|:..:.:||:|.|||.|:|:.| :|::..|..|.|.|
Zfish   404 MNPNFFLQGH--RRKLFLLVICIACFLIGLLMVTEGGLYVFQLFDYYSCSGMTLLLFAIAQSICI 466

  Fly   772 AWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAY 836
            .||||..||.:|:..|.|..|...::.||..:.|.:....::.||:.: .|...|..|.||.|.|
Zfish   467 GWFYGADRLYENIADMIGYHPLTLMKYCWKYITPIVCIGTFIFSLVKF-TPLKFNNTYEYPWWGY 530

  Fly   837 GIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRP 876
            ..||.|...|.:.:|.:.:...|.:.| |..:|:|....|
Zfish   531 AAGWWFTLSSTLLVPIWMIYAILVTPG-TLKQRLRVLCTP 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	219/542 (40%)
slc6a22.1	XP_005166076.1	SLC6sbd-TauT-like	30..569	CDD:271387	219/542 (40%)