Protein Alignment ine and Slc6a18

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_058859.2
• Gene: Slc6a18 / 29323
• RGDID: 69352
• Length: 615
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 212/645 - (32%)
• Similarity: 328/645 - (50%)
• Gaps: 118/645 - (18%)

  Fly   321 DSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFI 385
            |..:|:.||    :|:   |.||:|::|:|||::|||||:|||||:|:..|||.||:||.|.|..
  Rat     8 DPLVDIEDE----RPK---WDNKLQYLLSCIGFAVGLGNIWRFPYLCHTHGGGAFLIPYFIALVF 65

  Fly   386 CSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFK 450
            ..|||.::||::||...||.||....:.|...|.||....||||:|.||:.|:.:.:::|..||:
  Rat    66 EGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTILLWVLWFFLNSFQ 130

  Fly   451 TEMPW----IDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWE 511
            ..:||    :|.|......:|             .:|.|.| .|:..:.|.|:..:...|.::|:
  Rat   131 HPLPWSTCPLDLNRTGFVQEC-------------QSSGTVS-YFWYRQTLNITSDISNTGTIQWK 181

  Fly   512 LFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSE 576
            ||.||:..|..||....:.|:|:.||.||||.||::::.|.::|.:||.||.|||.:.|.|....
  Rat   182 LFLCLVACWTTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLTYLFTPNMKI 246

  Fly   577 LKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLG 641
            |:|..||::||:|.|.||.:.||..|:|||||:..||..:|.|.::.||.:|||...|..||.:|
  Rat   247 LQNPRVWLDAATQIFFSLSLAFGGHIAFASYNQPRNNCEKDAVTIALVNSMTSLYASITIFSIMG 311

  Fly   642 NLA-------LEQN---------------------------------------------TNVRDV 654
            ..|       |::|                                             .:..|.
  Rat   312 FKASNDYGRCLDRNILSLINEFDFPELSISRDEYPSVLMYLNATQPERVARLPLKTCHLEDFLDK 376

  Fly   655 IGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQD------GFPRW 713
            ...|||:.|:|:.:|:..||.|.:|:|:||.||..|||:|.|..:|.|:|.:.|      |.|:
  Rat   377 SASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLFDMGILPKGVPK- 440

  Fly   714 IKRHLGYHEIVVLFVCVISCL-FGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGT 777
             :...|    ||.|:|.:|.: |    .:|.|.|:.::.|.:|||:.::..||.:::.:...||.
  Rat   441 -ETMTG----VVCFICFLSAICF----TLQSGSYWLEIFDSFAASLNLIIFAFMEVVGVIHVYGI 496

  Fly   778 GRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWV--LSLINYHEPTYH--NGRY--------- 829
            .|...:::.|||:.||.|.:..|.|:.|.|||.|::  :.|:....|:|.  |.:|
  Rat   497 KRFCDDIEWMTGRRPSLYWQVTWRVVSPMLLFGIFLSYIVLLAQSSPSYKAWNPQYEHFPSREEK 561

  Fly   830 TYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNT-----LRPNIYECKIC 884
            .||.|......:.:....:.:||.|:...|..    :.:|.:||     |:|.  |.:.|
  Rat   562 LYPGWVQVTCVLLSFLPSLWVPGIALAQLLFQ----YRQRWKNTHLESALKPQ--ESRGC 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	204/619 (33%)
Slc6a18	NP_058859.2	SLC6sbd_B0AT3	16..591	CDD:212086	201/605 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810