Protein Alignment ine and snf-3

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_493910.2
• Gene: snf-3 / 173493
• WormBaseID: WBGene00004902
• Length: 600
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 201/579 - (34%)
• Similarity: 331/579 - (57%)
• Gaps: 33/579 - (5%)

  Fly   314 PLGVDDDDS-YLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLV 377
            ||..|:..: .|:.|..:.:  |.:..|..|..|:::.:.|:|||||||||||:|||:|||.|||
 Worm     8 PLPTDEAKAKELEQSQHSEE--PDRGQWTGKFDFLMSMVAYAVGLGNVWRFPYLCYKNGGGSFLV 70

  Fly   378 PYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSI 442
            .|.|...:.::|:..||::||||..:|.: .:..:||||:|.|:.:||::|:...|:.||:.:::
 Worm    71 VYMIFFCLAAVPIFLMEVTVGQYLQKGAM-EMWLMCPLFRGVGIGNVVIAFMCIAYFCVIVAWAM 134

  Fly   443 YYFFTSFKTEMPWIDCNNRWNTPDCWVPQR--------KGINASAPDTSRTPSEEFFENKVLQIS 499
            :|..:|.....||..|||.||...|...:.        |.:.|||...::|..|:|:|.:||..:
 Worm   135 FYMISSIAWVFPWETCNNYWNDATCVTGKENFTELARIKALVASAGGHTQTSVEQFWEKRVLHDT 199

  Fly   500 GGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAE 564
            |.:...|.::||||..:..|||:||||.||.|..:.|..||.|.||:|||.||::|.:||:||..
 Worm   200 GDISEFGGIQWELFFIMAAAWLIVYFALWKGITQARKFVYFCALFPYVLIFILLIRGLTLEGAGT 264

  Fly   565 GLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITS 629
            |:.|:.:|..:.|.:..||.:|.:|.|.|.|:.||::|:..|:||:|:|..:|.:.:..:|..||
 Worm   265 GIYFYLKPNATRLLDTAVWKDAGTQVFYSYGVGFGALIALGSHNKFNHNCFKDAITMCFINGCTS 329

  Fly   630 LLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNS 694
            :..|...||.||.::.....::.:::..|.|:.|:.||:..:.:|..|::||:||.|:..|||:|
 Worm   330 ITAGFAVFSILGYMSHVAQKDISEIVKPGVGLAFLAYPEVASNLPMKQVFAVLFFLMITILGLDS 394

  Fly   695 QFAIVEVVVTSIQDGFP---RWIKRHLGYHEIVVLFVCVISCLF----GMPNIIQGGIYYFQLMD 752
            |..::|.:.|:::|.||   ::.|:.||           |.|||    |:|.:...|.::..|.|
 Worm   395 QVCMMEGLFTALEDAFPILRKYKKQSLG-----------IFCLFFFCIGIPMVTHSGSHWLTLFD 448

  Fly   753 HYAAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSL 816
            .|.|| ..::|:.|.:::.:|:.:|...:.|.:.:|.|......:...|....|.....::|..:
 Worm   449 AYGASGYALLFVVFFEVVGLAYGFGAHNIRKALHEMIGVTLPKGIEYVWKFCAPATSLVLFVFCV 513

  Fly   817 INYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVIN-FLRSSGDTFWERIRNTL 874
            :.||...|.:|: .:|.||...||..:|.|::.|||||:.. |..:...|..||:|..|
 Worm   514 VYYHPVKYPDGK-DFPFWANAFGWFLSSCSMVVIPGYAIYYLFFTNKHLTLKERVRKGL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	195/555 (35%)
snf-3	NP_493910.2	SLC6sbd-TauT-like	30..571	CDD:271387	194/553 (35%)