Protein Alignment ine and Slc6a13

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_006237280.2
• Gene: Slc6a13 / 171163
• RGDID: 620788
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 630
• Identity: 245/630 - (38%)
• Similarity: 379/630 - (60%)
• Gaps: 46/630 - (7%)

  Fly   308 NPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGG 372
            |.:|.|...|      ::..:|...|:  ::.|.|||:|||:..|..:||||||||||:|||:||
  Rat    11 NGETKPVCPV------MEKVEEDGTLE--REQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGG 67

  Fly   373 GVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFK------GAGLASVVVSFLMS 431
            |.|.:||.|.||.|.||:.|:|.::||||.:|.|.|..::||:|:      |.|.||.::..|::
  Rat    68 GAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLN 132

  Fly   432 TYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQR--KGINASAPDTSRTPSEEFFENK 494
            .||.|::.::::|.|:||.|::||..|::.|||.:|...|:  ..:|.:: :.:.:|..||:|.:
  Rat   133 VYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKTNNSLNVTS-ENATSPVIEFWERR 196

  Fly   495 VLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTL 559
            ||:||.|:::.|.:||||..||:.||::.||..||.:||:.||.|||||||::::::|::|.|||
  Rat   197 VLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTL 261

  Fly   560 DGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAV 624
            .|||:|::|:..|..:.|.:..||::|.:|.|.|..|..|.:.:..|||||:||..||.||:..:
  Rat   262 PGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCIL 326

  Fly   625 NMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLC 689
            |..||.:.|...||.||.::.||...:.:|...|||:.|:.||:|:..:|::.|||..||||::.
  Rat   327 NSSTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVL 391

  Fly   690 LGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHY 754
            |||:|||..||.:||::.|.:|| :.|.....||::|.|.|:|...|:..:.:||:|.|||.|:|
  Rat   392 LGLDSQFVCVESLVTALVDMYPR-VFRKKNRREILILIVSVVSFFIGLIMLTEGGMYVFQLFDYY 455

  Fly   755 AAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLIN 818
            ||| :.::|:|..:.:.:||.||..|...|::.|.|..|...::.|||...|.:..|.::.|||.
  Rat   456 AASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIK 520

  Fly   819 YHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIYECKI 883
            |...|| |.:||||.|...:||:.|..|::|||.:::.. ||:......||:|..:.|
  Rat   521 YTPLTY-NKKYTYPWWGDALGWLLALSSMVCIPAWSIYK-LRTLKGPLRERLRQLVCP------- 576

  Fly   884 CGEHHCEHDYPEQEQFMLAQEMATVYKPTNP-----HLLNLGQKC 923
                  ..|.|::.|..|.       .|..|     .|..|...|
  Rat   577 ------AEDLPQKSQPELT-------SPATPMTSLLRLTELESNC 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	229/547 (42%)
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:382020	231/565 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820