Protein Alignment ine and Slc6a13

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001366036.1
• Gene: Slc6a13 / 14412
• MGIID: 95629
• Length: 602
• Species: Mus musculus
• Alignment Length: 637
• Identity: 247/637 - (38%)
• Similarity: 382/637 - (59%)
• Gaps: 53/637 - (8%)

  Fly   298 TTANELFDMVNPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWR 362
            ||:|   ....|..|....|::|.:.            .::||.|||:|||:..|..:|||||||
Mouse     8 TTSN---GETKPVCPAMEKVEEDGTL------------EREHWNNKMEFVLSVAGEIIGLGNVWR 57

  Fly   363 FPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVS 427
            |||:|||:|||.|.:||.|.||.|.||:.|:|.::||||.:|.|.|..::||:|:|.|.||.::.
Mouse    58 FPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIV 122

  Fly   428 FLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQR--KGINASAPDTSRTPSEEF 490
            .|::.||.|::.::::|.|:||.|::||..|::.|||.:|...|:  ..:|.:: :.:.:|..||
Mouse   123 SLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTS-ENATSPVIEF 186

  Fly   491 FENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVR 555
            :|.:||::|.|:::.|.:||||..||:.||::.||..||.:||:.||.|||||||::::::|::|
Mouse   187 WERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIR 251

  Fly   556 AVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVA 620
            .|||.|||:|::|:..|..:.|.:..||::|.:|.|.|..|..|.:.:..|||||:||..||.:|
Mouse   252 GVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIA 316

  Fly   621 VSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFF 685
            :..:|..||.:.|...||.||.::.||...:.:|...|||:.|:.||:|:..:|::.|||..|||
Mouse   317 LCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFF 381

  Fly   686 MLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQL 750
            |::.|||:|||..||.:||::.|.:|| :.|.....|:::|.|.|||...|:..:.:||:|.|||
Mouse   382 MVVLLGLDSQFVCVESLVTALVDMYPR-VFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQL 445

  Fly   751 MDHYAAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVL 814
            .|:|||| :.::|:|..:.:.:||.||.||...|::.|.|..|...::.|||...|.:..|.::.
Mouse   446 FDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLF 510

  Fly   815 SLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIY 879
            |||.|...|| |.:||||.|...:||:.|..|:||||.:::.. ||:......||:|..:.|
Mouse   511 SLIKYTPLTY-NKKYTYPWWGDALGWLLALSSMICIPAWSIYK-LRTLKGPLRERLRQLVCP--- 570

  Fly   880 ECKICGEHHCEHDYPEQEQFMLAQEMATVYKPTNP--------HLLNLGQKC 923
                      ..|.|::.|          .:||.|        .|..|...|
Mouse   571 ----------AEDLPQKNQ----------PEPTAPATPMTSLLRLTELESNC 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	230/541 (43%)
Slc6a13	NP_001366036.1	SLC5-6-like_sbd	32..575	CDD:382020	232/559 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2921
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.770