Protein Alignment ine and blot

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_061506640.1
• Gene: blot / 1275734
• VectorBaseID: AGAMI1_009973
• Length: 1013
• Species: Anopheles gambiae
• Alignment Length: 888
• Identity: 186/888 - (20%)
• Similarity: 319/888 - (35%)
• Gaps: 280/888 - (31%)

  Fly    85 PFRQTSSTTSLAAMA---AALHKQS--PLRHTSVRTRPSSEVLQ------PGQVLAN-------- 130
            |.:..||.||::.::   ...|:.|  .:..||.|.:....||.      |.:.||:
Mosquito     8 PKQSISSVTSMSFLSDENLTFHRFSDGTISFTSERKKSMQNVLDGGGGGAPMKTLASGGPNTKQP 72

  Fly   131 -QPTAAVST---STVTFTIDDCNEEGDAIPAAASVPAPVTMPAISPTPATLTCTTTTTM------ 185
             .|:.|:.|   ...:.||:...:.........|.|       |..|.|:....||.|:
Mosquito    73 CPPSTAIGTMDGGGQSHTIERTRKHSYTQATTGSSP-------IWTTNASFNNYTTNTITNSNRR 130

  Fly   186 -AGDSVAVSPLSMELKSRLGSHHSSMRSVVSGYLPGLSDSSGNLVGGVSMATSGLQAPNPLYMQP 249
             ||...:|:|:.               .|..|            .||.|..|:|:
Mosquito   131 HAGRPRSVAPVG---------------DVTDG------------EGGGSTTTAGI---------- 158

  Fly   250 QASLSGSSYHFHELAGNQIYSDVTSVRSLASIGIGSTDGRKLVIRRVPTTANELFDMVNPQTPPP 314
             .:||...|         :.|..|:..:.:.|..|||  .||:..:|  :||         |..|
Mosquito   159 -PTLSDLRY---------LSSPSTNPNNSSMIQNGST--VKLISTKV--SAN---------TVAP 200

  Fly   315 LGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPY 379
               .||.|             .:|..::..:.|:.|:..::...||.|||.. .:..|..|||||
Mosquito   201 ---SDDQS-------------NKQSRSSIFRGVILCLCLNLTFANVVRFPRE-LQLHGSAFLVPY 248

  Fly   380 CIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSV--IIGYSI 442
            .|:|.:..:|::.:|:|:||:.|:|. ..:.:..|..|||.|...:.|:|.:.:.|:  :|.. :
Mosquito   249 VILLLLVGLPVVLLEISLGQFLGQGS-AHMWRAAPFLKGASLVGRIASWLAAIWTSMQSVIAL-L 311

  Fly   443 YYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLE---- 503
            |....:||: :|..:|:           :...||..|          .:....:|.|.|.|
Mosquito   312 YIGMLAFKS-VPLRECS-----------KSVTINPQA----------IYNGYDVQQSSGQECLKL 354

  Fly   504 -----------YPGMMRWELFACLICAWLMVYFATWKSIKSSAKV-RYFTATFPFVLIIILMVRA 556
                       |.|:    |...||..|::....|     .|.|: |.....|.||.:::|:
Mosquito   355 TFLRPVWRSSLYFGL----LALSLILLWVISMVCT-----HSGKINRRSIYLFGFVALVLLI--- 407

  Fly   557 VTLDGAAEGLRFFFRPKWSELKNAN-------------------VWINAASQNFNSLGITFGSMI 602
                         |...|...|:.|                   ||.||..|...||.|.||::.
Mosquito   408 -------------FETGWEVTKSINEQYFPDLWPFHPESFADSTVWFNALVQVIYSLNIGFGAVP 459

  Fly   603 SFASYNKYNNNILRDTVAVSAVN-MITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGM--IFV 664
            .......|..:.::.:......| :||::.|..:.|        :.|.:..:.....|.:  :.|
Mosquito   460 VLTGKFLYKGDAIKTSFVYIFFNILITAIAVVFYVF--------QYNNSFTEAHPFYPELSALTV 516

  Fly   665 VYPQAMA---------KMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGY 720
            :|.:|::         ::..|..:.|:|        ::|..:||..:.||     .|.|::|..|
Mosquito   517 IYDRAISVQESDPTLQRLIPALSYTVIF--------ISSLVSIVIYIYTS-----TRIIRKHPNY 568

  Fly   721 HEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQM----IAIAWFYGTGRLS 781
                  .||:...:..:..::.....:.:::|    :..:..||.|.|    |.|.|.||:..|.
Mosquito   569 ------TVCLAGLVVAIAGLLCPNYIFPRILD----TRIVGALAVCAMIFEIILIIWVYGSKNLY 623

  Fly   782 KNVKQMTGKAPSFYLRSCWLVLG---PCLLFAI---WVLS------LINYHEPTYHNGRYTYPDW 834
            .:::...|:.    :...||.:.   |.||.|:   |.::      ||:|           :|.
Mosquito   624 TDLEFSLGRP----VLKAWLFIWGFIPVLLMALLCWWSITYYDNDLLIDY-----------FPK- 672

  Fly   835 AYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPN 877
                 |:...|||..|...|.:...:......:..|....:|:
Mosquito   673 -----WLPVVFSLSVIVLLACVEISKQVDYNIFSMIHGATKPS 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	127/603 (21%)
blot	XP_061506640.1	None