Protein Alignment ine and Slc6a20a

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_579830.2
• Gene: Slc6a20a / 113918
• RGDID: 621651
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 627
• Identity: 219/627 - (34%)
• Similarity: 317/627 - (50%)
• Gaps: 109/627 - (17%)

  Fly   310 QTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGV 374
            |.|.|    |:....||.      |.|.| |.|.:|||.|||.|:|||||||||||:|...|||.
  Rat    13 QRPGP----DEKRARDME------KARPQ-WGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGS 66

  Fly   375 FLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIG 439
            |||||.|:|.:..:|||::||:|||...:|.|||...:.|...|.|:|||||||.:|.||:||..
  Rat    67 FLVPYLIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINA 131

  Fly   440 YSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEY 504
            :..:|.|.||:..:||..|....|        |.|.:......|.|  :.|:..|.|.||..::.
  Rat   132 WGFWYLFHSFQDPLPWSVCPLNSN--------RTGYDEECEKASST--QYFWYRKTLNISPSIQE 186

  Fly   505 PGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFF 569
            .|.::||...||..||||||....:..:|:.||.||||..|:.::||.:||.:||.||..||.:.
  Rat   187 NGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTALMPYCVLIIYLVRGLTLHGATNGLMYM 251

  Fly   570 FRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGI 634
            |.||..:|.|...|||||:|.|.|||:.|||:|:|||||:.:|:..:..|.||.:|..||:...|
  Rat   252 FTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNDCQKHAVIVSVINSSTSIFASI 316

  Fly   635 FAFSTLG---------------------------------------------------------N 642
            ..||..|                                                         |
  Rat   317 VTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTASNLEEVKDYLASTYPNKYSEVFPHIRN 381

  Fly   643 LALEQ--NTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTS 705
            .:||.  ||.|:     |.|:.|:||.:|:..|..:|||:|::|||||.||:.|.......::|.
  Rat   382 CSLESELNTAVQ-----GTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTP 441

  Fly   706 IQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIA 770
            :.|.  :.|..:|. .|.:...||:|:|..||...::.|.|:|.:.:.|||:::::.:...:.||
  Rat   442 LTDS--KVISSYLP-KEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIA 503

  Fly   771 IAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDW- 834
            :.:.||..|...:::.|||:..::|.::.|..:.|.|:..:::..|.:|    ...|...|..|
  Rat   504 VCYVYGLRRFESDLRAMTGRPLNWYWKAMWAFVSPLLIIGLFIFYLSDY----ILTGTLQYQAWD 564

  Fly   835 -AYG--------------IGWMFASFSLICIPGYAVINFLRS 861
             ..|              ||.:.|| |.:|||..|:..|:|:
  Rat   565 ATQGQLVTKDYPPHALAVIGLLVAS-STMCIPLVALGTFIRN 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	211/600 (35%)
Slc6a20a	NP_579830.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		5/16 (31%)
		SLC5-6-like_sbd	26..601	CDD:444915	211/604 (35%)