Protein Alignment ine and Slc6a15

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_001239259.1
• Gene: Slc6a15 / 103098
• MGIID: 2143484
• Length: 729
• Species: Mus musculus
• Alignment Length: 613
• Identity: 188/613 - (30%)
• Similarity: 310/613 - (50%)
• Gaps: 109/613 - (17%)

  Fly   318 DDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCII 382
            ::.|:..:...|....:|.   |.:|:|::||.:|:||||||||||||:|.|:|||.:|:||.|:
Mouse    45 EEKDTDAEDGSEADDERPA---WNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLIL 106

  Fly   383 LFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFT 447
            |.:..|||.|:||||||...||.||....:.|...|.|.||.||.:.::.||:||||::::||..
Mouse   107 LLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWTLFYFSQ 171

  Fly   448 SFKTEMPWIDC------NNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPG 506
            ||:..:||..|      ::.:..|:|              ...:.:..::..:.|.|:..:...|
Mouse   172 SFQQPLPWDQCPLVKNASHTYVEPEC--------------EQSSATTYYWYREALDITSSISDSG 222

  Fly   507 MMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFR 571
            .:.|::..||:.||:||..|..|.|:||.|:.||::.||:|::|..::|::.|:|:.:|:|..|.
Mouse   223 GLNWKMTVCLLVAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFT 287

  Fly   572 PKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFA 636
            ||...:....||..||:|.|.:||:.||.:|:|:||||.:||...|.|.||.:|..||:|..:..
Mouse   288 PKLEMMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVV 352

  Fly   637 FSTLGNLA-------LEQNTN--------------------------------VRDVIG------ 656
            |:.||..|       :.||:.                                |.|:|.
Mouse   353 FAVLGFKANIVNEKCISQNSEMILKLLKMGNISWDVIPHHINLSAVTVEDYRLVYDIIQKVKEEE 417

  Fly   657 -------------------DGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVV 702
                               .|.|:.|:.:.:||...|.:..|:||||.||:.|||.|.|..:|.:
Mouse   418 FAVLHLNACQIEDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGI 482

  Fly   703 VTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQ 767
            :|.|.|.|.  :::     ||:.:..|:::...|:..:.:.|.|:..:.|.|:|::.::.:...:
Mouse   483 ITPIVDTFK--VRK-----EILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILE 540

  Fly   768 MIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLIN--YHEPTYH----- 825
            .||:::.||..:..:::..|.|.|||.|....|..:.|.:|..:.:.|::|  ...|.|:
Mouse   541 NIAVSFVYGIDKFIEDLTDMLGFAPSKYYYYMWKYISPLMLLTLLIASIVNMGLSPPGYNAWIKE 605

  Fly   826 ---NGRYTYPDWAYGIGWMFASFSLICI 850
               ....:||.|.     |...|||:.:
Mouse   606 KASEEFLSYPMWG-----MVVCFSLMVL 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	185/594 (31%)
Slc6a15	NP_001239259.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..61		2/15 (13%)
		SLC6sbd_SBAT1	61..640	CDD:212091	186/597 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820