Protein Alignment ine and Slc6a8

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_598748.1
• Gene: Slc6a8 / 102857
• MGIID: 2147834
• Length: 640
• Species: Mus musculus
• Alignment Length: 619
• Identity: 241/619 - (38%)
• Similarity: 364/619 - (58%)
• Gaps: 43/619 - (6%)

  Fly   301 NELFDMVNPQTPPPLGVDDDDSYLDMSDETAQL--------KPRQQHWANKMQFVLACIGYSVGL 357
            |.::.:...:...||.|...|......|..|.|        .|.::.|..:|.|:::|:|::|||
Mouse     8 NGIYSVSGDEKKGPLIVSGPDGAPAKGDGPAGLGAPGGRLAVPPRETWTRQMDFIMSCVGFAVGL 72

  Fly   358 GNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLA 422
            ||||||||:|||:||||||:||.:|..:..||:.|:|:|:||:...|.|. :..:||||||.|.|
Mouse    73 GNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSIN-VWNICPLFKGLGYA 136

  Fly   423 SVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKG--INASAPDTS-- 483
            |:|:.|..:|||.:::.:..||...||.|.:||..|.:.||||||....|..  .|||..:.:
Mouse   137 SMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCD 201

  Fly   484 -----RTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTAT 543
                 |:|..||:|||||::|.|||.||.:.||:..||:..|::|||..||.:||:.|:.|||||
Mouse   202 QLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTAT 266

  Fly   544 FPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYN 608
            ||:|::::|:||.|.|.||.:|:.::.:|.||:|.:..|||:|.:|.|.|..|..|::.:..|||
Mouse   267 FPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYN 331

  Fly   609 KYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKM 673
            ::|||..:|.:.::.:|..||...|...||.||.:|.||..::..|...|||:.|:.||:|:..|
Mouse   332 RFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLM 396

  Fly   674 PYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYH-----EIVVLFVCVISC 733
            |.|.|||.:||||||.|||:|||..||..:|.:.|..|      ..|:     ||.|...|.:..
Mouse   397 PVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLP------ASYYFRFQREISVALCCALCF 455

  Fly   734 LFGMPNII-----QGGIYYFQLMDHYAAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAP 792
            :..:..:.     :||:|.|||.|:|:|| .|:::.||.:.:.:||.||..|...::..|.|..|
Mouse   456 VIDLSMVTDVSGGKGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRP 520

  Fly   793 SFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVIN 857
            ..:::.||....|.:...|::.::: |:||..:|..|.||.|...:||.||..|::|:|.:.:..
Mouse   521 CPWMKWCWSFFTPLVCMGIFIFNIV-YYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGC 584

  Fly   858 FLRSSGDTFWERIRNTLRPNIYECKICGEHHCEH 891
            .||:.| |..||.::..:|      |.|.||.|:
Mouse   585 LLRAKG-TMAERWQHLTQP------IWGLHHLEY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	226/558 (41%)
Slc6a8	NP_598748.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		4/18 (22%)
		SLC6sbd_CT1	52..626	CDD:271397	232/575 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820