Protein Alignment ine and Slc6a20a

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: NP_631881.1
• Gene: Slc6a20a / 102680
• MGIID: 2143217
• Length: 592
• Species: Mus musculus
• Alignment Length: 598
• Identity: 211/598 - (35%)
• Similarity: 310/598 - (51%)
• Gaps: 89/598 - (14%)

  Fly   334 KPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVG 398
            |.|.| |.:.:|||.|||.|:|||||||||||:|...|||.|||||.|:|.:..:|||::||:||
Mouse     3 KARPQ-WGHPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVG 66

  Fly   399 QYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWN 463
            |...:|.|||...:.|...|.|:|||||||.:|.||:||..:..:|.|.||:..:||..|....|
Mouse    67 QRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSN 131

  Fly   464 TPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATW 528
                    ..|.:......|.|  :.|:..|.|.||..::..|.::||...||..||||||....
Mouse   132 --------HTGYDEECEKASST--QYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCIL 186

  Fly   529 KSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNS 593
            :..:|:.||.||||:.|:.::||.:||.:||.||..||.:.|.||..:|.|...|||||:|.|.|
Mouse   187 RGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFS 251

  Fly   594 LGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFS-------------------- 638
            ||:.|||:|:|||||:.:||..:..:.||.:|..||:...|..||
Mouse   252 LGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILL 316

  Fly   639 ------------TLGNLALEQN--------------TNVR--------DVIGDGPGMIFVVYPQA 669
                        |:.||...:|              .::|        |....|.|:.|:||.:|
Mouse   317 LTNSFDLEDGFLTVSNLEEVKNYLASTYPNKYSEVFPHIRNCSLESELDTAVQGTGLAFIVYTEA 381

  Fly   670 MAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCL 734
            :..|..:|||:|::|||||.||:.|.......::|.:.|.  :.|..:|. .|.:...||:|:|.
Mouse   382 IKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDS--KVISSYLP-KEAISGLVCLINCA 443

  Fly   735 FGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSC 799
            .||...::.|.|:|.:.:.|||:::::.:...:.||:.:.||..|...:::.|||:..|:|.:..
Mouse   444 VGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLRAMTGRTLSWYWKVM 508

  Fly   800 WLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDW--AYG--------------IGWMFASFSLI 848
            |..:.|.|:..:::..|.:|    ...|...|..|  ..|              ||.:.|| |.:
Mouse   509 WAFVSPLLIVGLFIFYLSDY----ILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVAS-STM 568

  Fly   849 CIPGYAVINFLRS 861
            |||..|:..|:|:
Mouse   569 CIPLVALGTFIRN 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	209/595 (35%)
Slc6a20a	NP_631881.1	SLC5-6-like_sbd	2..577	CDD:444915	209/592 (35%)