Protein Alignment ine and slc6a8

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_002935539.1
• Gene: slc6a8 / 100489909
• XenbaseID: XB-GENE-986840
• Length: 644
• Species: Xenopus tropicalis
• Alignment Length: 581
• Identity: 241/581 - (41%)
• Similarity: 356/581 - (61%)
• Gaps: 32/581 - (5%)

  Fly   335 PRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQ 399
            |.:..|.::|.|:::|:|::|||||||||||:|||:||||||:||.:|..:..||:.|:|:::||
 Frog    56 PERDTWTSQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILIAILGGIPIFFLEIALGQ 120

  Fly   400 YTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNT 464
            :...|.| |:..:.|||:|.|.||||:.|..:|||.:|:.:.:||...||...:||..|||.||:
 Frog   121 FMKAGSI-AVWNIAPLFQGIGFASVVIVFFCNTYYILILTWGVYYLVKSFSAVLPWSHCNNTWNS 184

  Fly   465 PDC--WVPQRKGINASAPDT-----------SRTPSEEFFENKVLQISGGLEYPGMMRWELFACL 516
            |||  ...|....|.:|..|           ..:|..||:|.|||::|.||:..|.:.|||..||
 Frog   185 PDCVDIFRQEDCTNGTANSTFGNLTCNELADKVSPITEFWEKKVLRLSSGLDDIGSINWELLLCL 249

  Fly   517 ICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNAN 581
            |..||:|||..||.:||:.|:.|||||||:|:::||:||...|.||.||:.::.:|.||:|..|.
 Frog   250 IGCWLLVYFCVWKGVKSTGKIVYFTATFPYVVLLILLVRGAMLPGATEGIIYYLKPDWSKLGTAQ 314

  Fly   582 VWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALE 646
            |||:|.:|.|.|..|..|::.:..|||::||:..:|...::.:|..||...|...||.||.:|.|
 Frog   315 VWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFILAVINSGTSFFAGFVVFSILGFMANE 379

  Fly   647 QNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFP 711
            |..::..|...|||:.|:.||:|::.||.|.||:.:||||||.|||:|||..||.::|:|.|..|
 Frog   380 QGVDISKVAESGPGLAFIAYPRAVSLMPVAPLWSALFFFMLLLLGLDSQFVGVEGLITAILDLLP 444

  Fly   712 -RWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAAS-VTIMFLAFCQMIAIAWF 774
             |:..|.  ..||.|...|.|..|..:..:.:||:|.|||.|:|:|| :|:::..|.|.:.:||.
 Frog   445 ARYYFRF--QREIAVAICCAIMFLIDLSMLTEGGMYVFQLFDYYSASGMTLLWQTFWQCVVVAWV 507

  Fly   775 YGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIG 839
            ||..|...::.:|.|..|..:::.||..:.|.:..||::.:||||...||:|. ||||.|...||
 Frog   508 YGADRFMDDIARMIGYRPFPWMKWCWSFVTPFVCMAIFLFNLINYKPLTYNNS-YTYPWWGEAIG 571

  Fly   840 WMFASFSLICIPGYAVINFL---RSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQE 897
            |.||..|::|:|    :.||   ..:..:..||.::..:|      |.|.||.|:..|:.:
 Frog   572 WGFALSSMLCVP----VTFLYKITCAKGSLRERWQHLTKP------IWGAHHLEYMAPDPD 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	233/556 (42%)
slc6a8	XP_002935539.1	SLC5-6-like_sbd	58..644	CDD:382020	240/579 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820