Protein Alignment ine and slc6a2

DIOPT Version :9

• Sequence 1: NP_001162871.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_017948962.2
• Gene: slc6a2 / 100486589
• XenbaseID: XB-GENE-486549
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 601
• Identity: 220/601 - (36%)
• Similarity: 348/601 - (57%)
• Gaps: 39/601 - (6%)

  Fly   316 GVDDDDSYLDMSDETAQL------KPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGV 374
            ||....|.:.:.|.:.|.      :..::.|..|:.|:|:.:|:||.|.||||||::|||:|||.
 Frog    36 GVQYTSSTVIVPDLSPQYEVPGEGQQEREQWGKKIDFLLSVVGFSVDLANVWRFPFLCYKNGGGA 100

  Fly   375 FLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIG 439
            ||:||.:.|.|..:||.:|||::|||...| ...:.::||||||.|...::::..:..||:|||.
 Frog   101 FLIPYTLFLIIAGMPLFYMELALGQYNREG-AATVWKICPLFKGVGYTVILIALYVGFYYNVIIA 164

  Fly   440 YSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDT-----SRTPSEEFFENKVLQI- 498
            :|:||..:||.:|:|||.|.|.||:.:|..|....::..:.:|     ..||:.||:|..||.:
 Frog   165 WSLYYLVSSFTSELPWIKCGNEWNSLNCTDPMLLNMSMISYNTKYSKFKTTPAAEFYERGVLHLH 229

  Fly   499 -SGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGA 562
             |.|:...|..||:|..|||...::::|:.||.:|:|.||.:.|||.|:|::.:|::|.:||.|:
 Frog   230 ESNGIHDLGQPRWQLTICLIVVLIVLFFSLWKGVKTSGKVVWITATLPYVVLFVLLIRGITLPGS 294

  Fly   563 AEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMI 627
            ::|:..:.......|.:|:|||:||:|.|.|||..||.:|:||||||::||..||.:..|.:|.:
 Frog   295 SKGISAYLHIDIKRLTDASVWIDAATQIFYSLGAGFGVLIAFASYNKFDNNCYRDALMTSTINCV 359

  Fly   628 TSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGL 692
            ||.:.|...||.||.:|.:.|.|:.||..:|.|::|::||:|::.:..:..|||:||.|||.||:
 Frog   360 TSFISGFAIFSILGYMAHKHNVNIEDVATEGAGLVFIIYPEAISTLAGSTFWAVVFFIMLLTLGI 424

  Fly   693 NSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAAS 757
            :|....:|.|:|.:.|.. ..:|||   .::..|.|..|:.:|.:..|..||||...|:|.:||.
 Frog   425 DSAMGGMEAVITGLADDI-SILKRH---RKLFTLLVAFITFIFALLCITNGGIYVLTLLDTFAAG 485

  Fly   758 VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLINYHEP 822
            .:|:|....:.|.::||||..|.|:::.:|.|..|..|.|.||..:.|..|..:.::|::.|...
 Frog   486 TSILFAVLIEAIGVSWFYGVDRFSEDIHRMLGFRPGLYWRLCWKFVSPAFLLFVVIVSIVTYKPL 550

  Fly   823 TYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPNIYECKICGEH 887
            .|  ..|.:|.||...||..|..|:..:|.|.:..||         .:|.:||..:..|..
 Frog   551 MY--DEYKFPPWANRTGWAIALSSMTLVPIYIIYKFL---------TMRGSLRERLAYCIT---- 600

  Fly   888 HCEHDYPEQEQFMLAQ 903
                  ||.|..::||
 Frog   601 ------PENEHHLVAQ 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	208/545 (38%)
slc6a2	XP_017948962.2	SLC5-6-like_sbd	63..622	CDD:382020	215/574 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010