Protein Alignment ine and slc6a15

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 614
• Identity: 196/614 - (31%)
• Similarity: 310/614 - (50%)
• Gaps: 102/614 - (16%)

  Fly   318 DDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCII 382
            ||.|...|: :|.:.:...:..|.:|:|::||.:|:||||||||||||:|.|:|||.:||||.|:
 Frog    43 DDVDKDRDI-EEGSDIDDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLIL 106

  Fly   383 LFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFT 447
            |.:..||:.|:||||||...||.||....:.|...|.|.||.:|...::.||:||||:|::||..
 Frog   107 LLLIGIPVFFLELSVGQRIRRGSIGVWNYISPKMGGIGFASCIVCLFVALYYNVIIGWSLFYFSQ 171

  Fly   448 SFKTEMPWIDC---NNRWNT---PDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPG 506
            ||:..:||..|   .|..||   |:|              ...:.:..::..:.|.||..:...|
 Frog   172 SFQHPLPWDQCPLVKNASNTFVEPEC--------------EKSSATTYYWYREALNISNSITEGG 222

  Fly   507 MMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFR 571
            .:.|::..||:.||::|..|..|.|:||.||.||::.||:|::...:|||:.|:|:.:|:|..|.
 Frog   223 GLNWKMTLCLLAAWILVCLAMIKGIQSSGKVMYFSSLFPYVVLTCFLVRALLLNGSVDGIRHMFT 287

  Fly   572 PKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFA 636
            ||...:....||..||:|.|.:||:.||.:|:|:||||.:||...|.|.||.:|..||:|..:..
 Frog   288 PKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVV 352

  Fly   637 FSTLGNLA-------LEQNT---------------NVR--------------------------- 652
            |:.||..|       :.:||               ||.
 Frog   353 FAVLGFKANIMNENCISKNTVKIVKYLEAGNLSWSNVPHHVNFSSMSAQDYNLVYYIFQKIKEEE 417

  Fly   653 -DVIG--------------DGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVV 702
             |.:|              .|.|:.|:.:.:||...|.:..|:||||.||:.|||.|.|..:|.:
 Frog   418 FDSLGLDSCQIEDELNKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGI 482

  Fly   703 VTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQ 767
            :|.|.|.|.  :::     |.:.:..|:::...|:..:.:.|.|:..:.|.|:|::.::.:...:
 Frog   483 ITPIVDTFK--VRK-----EPLTVGCCLLAFCIGLLFVQRSGNYFVTMFDDYSATLPLLIVVILE 540

  Fly   768 MIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLI--NYHEPTYH----- 825
            .:||||.||..:...::|.|.|..|..|....|..:.|.||..:.:.|::  .:..|.|:
 Frog   541 NVAIAWVYGIDKFMDDLKDMLGFTPYKYYYYMWKYISPVLLTILLMASIVQMGFSPPGYYAWIAE 605

  Fly   826 ---NGRYTYPDWAYGIGWMFASFSLICIP 851
               ..|.:||.|...:......|:|:.:|
 Frog   606 KASEERISYPPWGLAVCISLIVFALLPVP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	191/595 (32%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:444915	191/595 (32%)