Protein Alignment ine and slc6a19a.2

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_002665492.2
• Gene: slc6a19a.2 / 100334171
• ZFINID: ZDB-GENE-141210-16
• Length: 647
• Species: Danio rerio
• Alignment Length: 646
• Identity: 191/646 - (29%)
• Similarity: 322/646 - (49%)
• Gaps: 111/646 - (17%)

  Fly   340 WANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRG 404
            |.||.|::|.|:|:.|||||||||||:|...|||.|::|:.|:|.:..||||.:|.::||...||
Zfish    36 WDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRRG 100

  Fly   405 PIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMPWIDC--NNRWNTPDC 467
            .:|....:.|...|.|:||::|||::..||:.||.:.::|||.||:..:||..|  |.
Zfish   101 SVGVWRSINPYLLGVGIASMLVSFIVGMYYNTIIAWVMWYFFNSFQDPLPWSQCPING------- 158

  Fly   468 WVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIK 532
               .|.|..:....:|  |.:.|:..|.|..:..:|..|.::|.:...|:|||.:::....:.|:
Zfish   159 ---SRTGFVSECERSS--PVDYFWYRKTLNTTPHIEDSGGLQWWMVLSLLCAWTVLWVCCIRGIE 218

  Fly   533 SSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGIT 597
            ::.|..|.|:|.|::::.|.::|.:||.|:..|::|.|.|..:||.:...|::|.:|.|.|..:.
Zfish   219 TTGKAVYITSTLPYLVLTIFLIRGLTLKGSVSGIKFLFTPDVNELLDPQTWLDAGAQVFFSFSLA 283

  Fly   598 FGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQ-----NTNVRDVIG- 656
            ||.:|:|:|||..:||..:|.|.:|.:|.:||:...|..:|.:|..|.|:     |.|:..::.
Zfish   284 FGGLIAFSSYNSVHNNCEQDAVIISIINGMTSIYAAIVIYSIIGFRATERFDDCLNGNILSLLNA 348

  Fly   657 ----------------------------------------------DGPGMIFVVYPQAMAKMPY 675
                                                          :|.|:.|:|:.:|:.|||.
Zfish   349 FDLPEGSIIEGNYTEAIQQLNISRPDIIQELQLKTCDMQTFLSQGVEGTGLAFIVFTEAITKMPV 413

  Fly   676 AQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQ--DGFPR-WIKRHLGYHEIVVLFVCVISCLFGM 737
            :.||:|:||.||.||||::.|..:|.||..:|  |..|: |.|      |.....|||:|..|.:
Zfish   414 SPLWSVLFFIMLFCLGLSTMFGSIEGVVVPLQDLDILPKNWPK------EAYTALVCVVSFAFAI 472

  Fly   738 PNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLV 802
            ......|.|:..|.|.:|.|:.::.:|||:|:|:::.||..|.:.::|.|.|..|:.:.::.|.:
Zfish   473 IFAQGSGEYWLALFDGFAVSIPLLIIAFCEMMAVSYVYGIDRFNDDIKFMIGHKPNIFWQATWRL 537

  Fly   803 LGPCLLFAIWV----------LSLINYHEPTYHN----GRYTYPDWAYGIGWMFASFSLICIPGY 853
            :.|.::..|::          |:.|.: :|...|    ....||.|...|.::.|...::.||..
Zfish   538 ISPLIVLVIFLFYFVTTVSKKLTYIAW-DPESENFPTLSVLPYPGWISAIIFILAGIPVLVIPTV 601

  Fly   854 AVINFLRSSGDTFWERIRNTLRPNIYECKICGEHHCEHDYPEQEQFMLAQEMATVYKPTNP 914
            |::..:|:..                 ||....|..|..|...::..:.:|.    :..||
Zfish   602 ALVRLIRNRC-----------------CKKEETHATETPYSISDRVQMMEET----EQNNP 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	183/606 (30%)
slc6a19a.2	XP_002665492.2	SLC5-6-like_sbd	33..613	CDD:444915	183/612 (30%)