Protein Alignment ine and slc6a8l

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_012815966.1
• Gene: slc6a8l / 100127575
• XenbaseID: XB-GENE-5768780
• Length: 654
• Species: Xenopus tropicalis
• Alignment Length: 637
• Identity: 250/637 - (39%)
• Similarity: 374/637 - (58%)
• Gaps: 59/637 - (9%)

  Fly   306 MVNPQTPPPLGVDDDDSYLDMSDETAQLK---PRQQHWANKMQFVLACIGYSVGLGNVWRFPYMC 367
            ::.|...|.:|               |:|   |.::.|..:|.|:::|:|::|||||||||||:|
 Frog    42 VIAPLVVPSMG---------------QVKIPIPERETWTRQMDFIMSCVGFAVGLGNVWRFPYLC 91

  Fly   368 YKSGGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMST 432
            ||:||||||:||.:|:|:..||:.|:|:::||:..:|.|.| ..:.|||||.|.||:|:.|..:|
 Frog    92 YKNGGGVFLIPYLLIVFVGGIPVFFLEIALGQFMKQGGIAA-WNIAPLFKGLGFASMVIVFFCNT 155

  Fly   433 YYSVIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDC----WVPQ-RKGINASAPDT---------- 482
            ||.:|:.:.:||...||...:||..|.|.||:.:|    .|.. ..|..|:..|:
 Frog   156 YYIMILVWGLYYLVHSFTNTLPWATCGNPWNSKECTEVFLVDHCNNGSLANVTDSGTLVNISCDA 220

  Fly   483 ---SRTPSEEFFENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATF 544
               .|:|..||:|.|||||||||..||.:.|::..||:..|::|||..||.:||:.||.||||.|
 Frog   221 LVNKRSPVIEFWERKVLQISGGLNEPGQLNWQMILCLMATWVIVYFCIWKGVKSTGKVVYFTALF 285

  Fly   545 PFVLIIILMVRAVTLDGAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNK 609
            |:|::|:|:...|||.||.:|:.::.:|.||:|..|.|||:|.:|.|.|..|..|::.:..|||:
 Frog   286 PYVVLIVLLAHGVTLPGALDGIVYYLKPNWSKLAEAQVWIDAGTQIFFSYAIGLGALTALGSYNR 350

  Fly   610 YNNNILRDTVAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMP 674
            ::||..||...::|:|..||...|...||.||.:|.||..::..|...|||:.|:.||:|:..||
 Frog   351 FHNNCYRDAYILAAINSTTSFFAGFVVFSVLGFMASEQGVHISKVAESGPGLAFIAYPKAVTLMP 415

  Fly   675 YAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGY--HEIVVLFVCVISCLFGM 737
            :|.:||.:||||||.|||:|||..||..:|.|.|.||:.|.   |:  .|:.....|::..:..:
 Frog   416 FAPIWAALFFFMLLILGLDSQFVGVEGFITGIMDLFPQPIN---GFVRREVTAALCCLVCFIIDL 477

  Fly   738 PNIIQGGIYYFQLMDHYAAS-VTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWL 801
            ..:.:||:|.|||.|:|:|| :|:::.||.:.:.|||.||..|...::.:|.|..|..|::.||.
 Frog   478 SMVTEGGMYVFQLFDYYSASGITLLWQAFWECVVIAWVYGADRFMDDIARMIGYRPLPYMKWCWS 542

  Fly   802 VLGPCLLFAIWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTF 866
            ||.|.:...|:|..::|| :|..:|..|.||.|...|||..|..|::|||...|...|||.|.
 Frog   543 VLTPLVCVGIFVFHVVNY-KPLTYNKSYVYPWWGEAIGWSLALASMLCIPLTVVCKMLRSKGS-- 604

  Fly   867 WERIRNTLRPNIYECKICGEHHCEHDYPEQEQFMLA--------QEMATVYK 910
               :|.  |.::....:.|.||.|:..||.|..:|.        :|.||:::
 Frog   605 ---LRE--RWHLLTTPVWGHHHLEYLTPEAETKLLPPDTLVTANKEKATLFE 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	232/559 (42%)
slc6a8l	XP_012815966.1	SLC6sbd_CT1	61..654	CDD:271397	244/603 (40%)