Protein Alignment ine and slc6a14

DIOPT Version :10

• Sequence 1: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Sequence 2: XP_002939712.3
• Gene: slc6a14 / 100127180
• XenbaseID: XB-GENE-480827
• Length: 634
• Species: Xenopus tropicalis
• Alignment Length: 631
• Identity: 244/631 - (38%)
• Similarity: 366/631 - (58%)
• Gaps: 63/631 - (9%)

  Fly   321 DSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFI 385
            :|:....||..:    :.:|:.|..::|:.|||:|||||||||||:.||:|||.||:||.|:|.:
 Frog    20 ESHSGSGDENKE----RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLAYKNGGGAFLIPYTIMLAL 80

  Fly   386 CSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFK 450
            ..:||.|:|.|:||::..||: .:.:..|:.:|.|:..|:|:..:|.||::||.||:||.|.||:
 Frog    81 AGLPLFFLECSMGQFSSSGPV-LVWRAVPILQGVGITMVLVTTFVSIYYNIIIAYSLYYMFASFQ 144

  Fly   451 TEMPWIDCNNRWNTPDC----------------------WVPQRKGI---NASAPDTSRTPSEEF 490
            |.:||.|| ..|....|                      ||.:|...   |:...:....||:::
 Frog   145 TILPWSDC-FAWADEKCSKVTRGFCNVSLSNNTVAYNLTWVKERNLTCIENSIVMEDVDLPSKQY 208

  Fly   491 FENKVLQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVR 555
            :|...|::||||:..|.:.|.|..||:.||::|..|.:|.||||.||.||||.||::::|||:||
 Frog   209 WEKVTLRLSGGLDETGEIVWYLALCLLLAWIIVGAALFKGIKSSGKVVYFTAIFPYIVLIILLVR 273

  Fly   556 AVTLDGAAEGLRFFFRPK--WSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDT 618
            ..||:||..|:.::...|  .::|..|.||.:||:|.|.||...:|.:|:.:||||::||...|.
 Frog   274 GATLEGAFNGIDYYIGTKSNITKLMEAEVWKDAATQIFFSLSTAWGGLIALSSYNKFHNNCYSDA 338

  Fly   619 VAVSAVNMITSLLVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMF 683
            :.|...|.:||:..|...||.||::|...:..|.:|:..|.|:.|:.||:|:||:|.:.||:.:|
 Frog   339 IVVCVTNCLTSVFAGFAIFSILGHMAFVTDKPVPEVVDSGFGLAFIAYPEALAKLPISPLWSFLF 403

  Fly   684 FFMLLCLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYF 748
            |||||.|||:||||::|.::|||||.||:.:||   ....|.:..|||..|.|:..:.|.|||:.
 Frog   404 FFMLLTLGLDSQFAMIETIITSIQDAFPQMMKR---MRIPVTIGCCVILFLLGLLCVTQSGIYWV 465

  Fly   749 QLMDHYAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTG-KAPSFYL--RSCWLVLGPCLLFA 810
            .|:|::.....|:|.|..:::.|.|.||..|..|:::.|.| |..:|::  |:||.|:.|.||.|
 Frog   466 NLIDYFCGGWAILFSAVLELVGINWIYGGNRFIKDIEMMIGEKHWTFWIWWRACWFVVSPLLLTA 530

  Fly   811 IWVLSLINYHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLR 875
            |.:.|||.:|.|||  |...||.|...|||....|.||.||..||:..:|:.|:.
 Frog   531 ILLWSLITFHSPTY--GSVVYPTWGTAIGWCMICFCLIWIPIVAVLKIIRAKGNV---------- 583

  Fly   876 PNIYECKIC---GEHHCEHDYPEQEQFML------AQEMATVYKPT 912
              :..||..   |....:| ..|:.:.||      |:|:.||.|.|
 Frog   584 --LQTCKAAQNWGPALSQH-RGERYKHMLDSKQAHAEELPTVSKLT 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	228/568 (40%)
slc6a14	XP_002939712.3	SLC6sbd_ATB0	32..628	CDD:271391	241/615 (39%)