Protein Alignment FIG4 and SAC1

DIOPT Version :10

• Sequence 1: NP_608841.1
• Gene: FIG4 / 33658
• FlyBaseID: FBgn0031611
• Length: 858
• Species: Drosophila melanogaster
• Sequence 2: NP_012710.1
• Gene: SAC1 / 853668
• SGDID: S000001695
• Length: 623
• Species: Saccharomyces cerevisiae
• Alignment Length: 510
• Identity: 133/510 - (26%)
• Similarity: 228/510 - (44%)
• Gaps: 78/510 - (15%)

  Fly    80 KVTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRV---NEVTSQRPPHPHED 141
            :|.....::||::.....|.::....:.......|:.|.:....:|..   :.:.|:      |.
Yeast    51 EVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFNSRIDSE------EA 109

  Fly   142 RYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGAKVDLDRDEPLPDWNTLTSNVDKAHER 206
            .|.::.:.....|.|||||:||||.:||.||.    ||         |...|.|
Yeast   110 EYIKLLELHLKNSTFYFSYTYDLTNSLQRNEK----VG---------PAASWKT----------- 150

  Fly   207 VDYAFRSDSRKRFVWNAYLLQPMEGIMLKD-----WLLEVTHGFVSQSCISIFGRHVNVCLVARR 266
                    :.:||.||.||.:.:.....:|     ::..|.:|:.......:....:.:.|:.||
Yeast   151 --------ADERFFWNHYLTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRR 207

  Fly   267 SSRFAGTRFLKRGANFQGDVANEVETEQIV------SDGQRICAFTQMRGSIPSHWSQDISKMVP 325
            |...||||:.:||.:..|:|.|..|||||:      |:...:.:|.|.|||:|.:|: :|:.:..
Yeast   208 SIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWA-EINNLKY 271

  Fly   326 KPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNLVKKRERRKHESIISKELEYSIRYLNQFLP 390
            ||.:.|.  :........||::....|| ...::|||   .::.||..:.:..|..:..||.  |
Yeast   272 KPNLVLG--ENSLDATKKHFDQQKELYG-DNYLVNLV---NQKGHELPVKEGYESVVHALND--P 328

  Fly   391 PPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESI-VQMTGMFFKAAGSEPGL------QTGIVRT 448
            ..|   :::||...:.|....:.::.|..|.|.: :.....|.|...|....      |..:|||
Yeast   329 KIH---YVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRT 390

  Fly   449 NCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKL-EFDSDCVTMLENLYEEHGDTLALQYGGS 512
            ||:|||||||..|..:.:..|..:.|....|.:... |.::..:|..:||:.::.|.:::.|.|:
Yeast   391 NCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSVAYSGT 455

  Fly   513 QLVHRIKT-YRKTAPWGSQG--SDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKP 564
               ..:|| :.:|......|  :|.:.:.||||.|.::|..:|.|.:||||.::|
Yeast   456 ---GALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	Syja_N	85..407	CDD:460545	83/335 (25%)
SAC1	NP_012710.1	COG5329	3..578	CDD:227637	133/510 (26%)