DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FIG4 and ATSAC1

DIOPT Version :9

Sequence 1:	NP_608841.1	Gene:	FIG4 / 33658	FlyBaseID:	FBgn0031611	Length:	858	Species:	Drosophila melanogaster
Sequence 2:	NP_173676.2	Gene:	ATSAC1 / 838868	AraportID:	AT1G22620	Length:	912	Species:	Arabidopsis thaliana

Alignment Length:	941	Identity:	269/941 - (28%)
Similarity:	422/941 - (44%)	Gaps:	229/941 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SIQKVVLYETRARLYLVGSNNRETRFRLLTIDRLAHNRLSIEENANEFNSLEIRRFVASLS---- 76
            :::|..|||||||.|||||:..:..||:|.|||...:.|:|.|:...::..||:..:..::
plant    33 ALEKFKLYETRARFYLVGSDRNKRFFRVLKIDRSEPSELNISEDPVVYSPQEIKSLLQRIAEGNR 97

  Fly    77 ---GSPKVTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVNEVTSQR--PP 136
               |...|...||:.|..:|:|.|||:|||||:....|..|.:|.|.::.|:.|...|.|.  ..
plant    98 ATGGLAFVAKVYGIAGCAKFMESYYLVLVTKRRQIGCICGHAIYAIDESQMISVPHATIQSDVAN 162

  Fly   137 HPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGAKVDLDRDEPLPDWNTLTSNVD 201
            ...|.|||::..::||..:|::||:|.:.::||.|..:....|...|               |:
plant   163 SKTELRYKKLLSSVDLTKDFFYSYTYPIMQSLQKNVLSSGEEGMPYD---------------NI- 211

  Fly   202 KAHERVDYAFRSDSRKRFVWNAYLLQPMEGIMLKD-WLLEVTHGFVSQSCISIFGRHVNVCLVAR 265
                             ||||:||.||:....... |.|.:.||...|..:||:||..:|.||:|
plant   212 -----------------FVWNSYLTQPIRSRCNNTIWTLALVHGHFKQIRLSIYGRDFSVTLVSR 259

  Fly   266 RSSRFAGTRFLKRGANFQGDVANEVETEQIVSDGQ------RICAFTQMRGSIPSHWSQDISKMV 324
            ||..|||||:||||.|.:|.|||:|||||:|.|.:      ::.:..|||||||..|||:.|:..
plant   260 RSRHFAGTRYLKRGVNDRGRVANDVETEQLVLDDEAGSCKGKMSSVVQMRGSIPLFWSQEASRFS 324

  Fly   325 PKPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNLVKKRERRKHESIISKELEYSIRYLNQFL 389
            |||.|.|...||..::..:|||.|:..||.|:|:|||:|..|:|..|.::.:|...::.|||...
plant   325 PKPDIFLQRYDPTYESTKMHFEDLVNRYGNPIIVLNLIKTVEKRPREMVLRREFANAVGYLNSIF 389

  Fly   390 PPPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESIVQMTGMFF---------KAA---------- 435
            ...:.:|.||:|..:.::....||:..|...|...:.:||::|         ||:
plant   390 REENHLKFIHWDFHKFAKSKSANVLAVLGAVASEALDLTGLYFSGKPKIVKKKASQLSHANTARE 454

  Fly   436 ---------------------------------------------GSEPGLQTGIVRTNCVDCLD 455
                                                         .|.|..|:|::||||:||||
plant   455 PSLRDLRAYSAELSRGESANDILSALANREKEMKLTQQKKDEGTNSSAPRYQSGVLRTNCIDCLD 519

  Fly   456 RTNSAQFAIGKCALGHQLERLGFVKSAKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHRIKT 520
            |||.||:|.|..|||.||..:|...:.|::.||.....|.::|:..||.||.||||| ..|....
plant   520 RTNVAQYAYGLAALGRQLHAMGLSDTPKIDPDSSIAAALMDMYQSMGDALAQQYGGS-AAHNTVF 583

  Fly   521 YRKTAPW--GSQGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKPSLTKQGPPIWELQTDYDMH 583
            ..:...|  .:|..:.::::.||||||::|.|||.:||||||.::|...|  |.:|||.:||.:|
plant   584 PERQGKWKATTQSREFLKSIKRYYSNTYTDGEKQDAINLFLGYFQPQEGK--PALWELDSDYYLH 646

  Fly   584 NAFVPRADSKAITDWVRHKVRACLPYSCADSNKLVKELFRVHSSGLEMIDAYSNYHQSFKWTDFS 648
                                                    |...|.::            :.|..
plant   647 ----------------------------------------VSGIGDDI------------FPDIG 659

  Fly   649 -EHIAFEISQLA--LRYMPTFRTNFS-----PFQRQIQTSRKARQNP---SMTGQSSTGSMNSNS 702
             :.||..:|.:.  |..:|.||.:||     .|.:.|:.:..:.:|.   |.|.|...|    |:
plant   660 VQSIAKPMSGIGVNLAPVPAFRDDFSRKKLTSFDKLIEQTCSSIKNVRLCSETDQRPGG----NT 720

  Fly   703 SSSSEGDDSSSDEELSASF---AEKEANQTESTEPAAATLATGLPSMEEIYG-CTINPPSKQSM- 762
            .|:....|::..:..|.::   :.|....:.:|:..|.....|:.|.|.:.. |.::..||...
plant   721 GSTGVAPDAAEIQLKSPNWLFGSRKPEESSSATKSGADDSEKGVTSTERVNDFCNLDWLSKSDRH 785

  Fly   763 --AVYKKYVQMGKLSSGGARPAQTAVAQRDQELAKIMRGITLRPLSDYGTDSYLSVRPPVVPRKS 825
              .::::|:.:...:........|.:..:| |.::|.|.
plant   786 QGDIFQRYLSITSTNEANGWYGGTLLGDQD-ENSEIYRH-------------------------- 823

  Fly   826 LTIYAEYCRTRSTFNAVPKLEEFDVLYQYVQ 856
               ||::|:       .|.:|.|:..:::.|
plant   824 ---YAQFCQ-------CPAMEPFENDHEFEQ 844

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	COG5329	19..599	CDD:227637	224/661 (34%)
FIG4	NP_608841.1	Syja_N	85..407	CDD:280532	122/330 (37%)
ATSAC1	NP_173676.2	Syja_N	109..407	CDD:396798	122/330 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	211	1.000	Domainoid score	I788
eggNOG	1	0.900	-	-		E1_COG5329
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	396	1.000	Inparanoid score	I479
OMA	1	1.010	-	-		QHG58176
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002534
OrthoInspector	1	1.000	-	-		otm2882
orthoMCL	1	0.900	-	-		OOG6_101803
Panther	1	1.100	-	-	LDO	PTHR45738
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1658
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830