DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FIG4 and AT1G17340

DIOPT Version :9

Sequence 1:	NP_608841.1	Gene:	FIG4 / 33658	FlyBaseID:	FBgn0031611	Length:	858	Species:	Drosophila melanogaster
Sequence 2:	NP_173177.2	Gene:	AT1G17340 / 838305	AraportID:	AT1G17340	Length:	785	Species:	Arabidopsis thaliana

Alignment Length:	783	Identity:	241/783 - (30%)
Similarity:	376/783 - (48%)	Gaps:	139/783 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PNIVFNPLISSIQKVVLYETRARLYLVGSNNRETRFRLLTIDRLAHNRLSIEENANEFNSLEIRR 70
            |.::..|:   :||..||.|.:..||:|.:..::..|:|.|||...|.|::.|:...:...|:|.
plant    11 PELIDLPV---LQKFKLYATPSNFYLIGRDENKSFRRILKIDRRDQNELNLFEDPTRYTKDEMRE 72

  Fly    71 FVASL-------SGSPKVTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVN 128
            ....:       .|...:|:.||::|||||||.||:||:||||....|..|.||.|.::.|:.:
plant    73 LKRRMIVGNEESGGFKAITTCYGIIGFVRFLEPYYMLLITKRKKVGEICGHTVYGIAESQMIAI- 136

  Fly   129 EVTSQRPPHPH----------EDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGAKVD 183
                   |||.          |.|||::...:||..||||||:|.|..:||.|      :|   :
plant   137 -------PHPSIQSKVAKSEAELRYKKLLSVVDLSKNFYFSYTYHLMYSLQKN------IG---N 185

  Fly   184 LDRDEPLPDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLLQPMEGIMLKD-WLLEVTHGFVS 247
            .:|..|              |:..          .||||::|.:.:..|:... |.:.:.:||..
plant   186 TERGNP--------------HDNT----------MFVWNSFLTREIRKILQNSIWTVALIYGFFQ 226

  Fly   248 QSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSD----GQR--ICAFT 306
            |:..|:.|......::||||..:||||:|:||.|..|.|||:||||||||.    ||:  |.:..
plant   227 QTKCSVSGEKFVFTIIARRSRHYAGTRYLRRGVNDIGRVANDVETEQIVSKVVPAGQKIPITSVV 291

  Fly   307 QMRGSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNLVK--KRERRK 369
            |:|||||..|||:.|...|:|:|.|:..|...:....||:.|...||..:|:|||:|  ..|::.
plant   292 QVRGSIPLFWSQEASVFNPQPEIILNKKDANYEATQHHFQNLRQRYGNRIIILNLLKTVTGEKKH 356

  Fly   370 HESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESIVQMTGMFFKA 434
            .|:|:..|...:||::|:.:...||:|.||||:::..:.........|.|.:...:::|.:|:..
plant   357 RETILRGEFAKTIRFINKGMDREHRLKAIHFDLSKHYKKGADGAFNHLCIFSRKSLELTDLFYCK 421

  Fly   435 AGSEPG-----------------------------------LQTGIVRTNCVDCLDRTNSAQFAI 464
            |.|..|                                   ||.|::||||:|||||||.||:|.
plant   422 APSGVGAEEVIYDSFFNNPIPSQDEEASSPEKEDMKADIFLLQNGVLRTNCIDCLDRTNFAQYAH 486

  Fly   465 GKCALGHQLERLGFVKSAKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHRIKTYRKTAPWG- 528
            |..:|||||..||......::.::.....|.:.|::.|:|||:|||||: .|..........|.
plant   487 GLVSLGHQLRTLGISGPPVVDLNNPLAIELMDAYQKMGNTLAMQYGGSE-AHSKMFCDLRGNWNM 550

  Fly   529 -SQGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKPSLTKQGPPIWELQTDYDMHNAFVPRADS 592
             .:..|:...:.|||||.:.|::||::||:|||.::|.|.:  |.:|||  |.|.||  :.|:.|
plant   551 VMRQRDIFTAVRRYYSNAYQDSDKQNAINVFLGHFRPRLGR--PALWEL--DSDQHN--IGRSGS 609

  Fly   593 KAITDWVRHKVRACLPYS-CADSNKLVKELFRVHSSGLEMIDAYSNYHQSFKWTDFSEHIAFEIS 656
            ....:.:|..:|.....: ..|.:..::||.|.:|.     ..|...:.....|:. |...:|..
plant   610 NLDIENMRPLIRRSFSDNIIMDCDLNLEELVRENSQ-----PTYEGLNGGVSGTNL-EFPFYETE 668

  Fly   657 QLALRYMPTFRTNFSPFQRQIQTSRKARQNPSMTGQSSTGSMNSNSSSSSEGDDSSSDEELSASF 721
            ..:|.::...|                  |..:..::.:|.|...|||:|:....:.....|.|:
plant   669 PASLSFLSVMR------------------NEELMRETGSGQMFQGSSSNSDSHRPNDIPGFSHSY 715

  Fly   722 AEK 724
            ..|
plant   716 VTK 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	COG5329	19..599	CDD:227637	215/642 (33%)
FIG4	NP_608841.1	Syja_N	85..407	CDD:280532	125/340 (37%)
AT1G17340	NP_173177.2	Syja_N	94..394	CDD:396798	125/340 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	211	1.000	Domainoid score	I788
eggNOG	1	0.900	-	-		E1_COG5329
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	396	1.000	Inparanoid score	I479
OMA	1	1.010	-	-		QHG58176
OrthoDB	1	1.010	-	-		D359616at2759
OrthoFinder	1	1.000	-	-		FOG0002534
OrthoInspector	1	1.000	-	-		otm2882
orthoMCL	1	0.900	-	-		OOG6_101803
Panther	1	1.100	-	-	O	PTHR45738
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1658
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840