Protein Alignment FIG4 and Sacm1l

DIOPT Version :10

• Sequence 1: NP_608841.1
• Gene: FIG4 / 33658
• FlyBaseID: FBgn0031611
• Length: 858
• Species: Drosophila melanogaster
• Sequence 2: NP_001344414.1
• Gene: Sacm1l / 83493
• MGIID: 1933169
• Length: 609
• Species: Mus musculus
• Alignment Length: 584
• Identity: 164/584 - (28%)
• Similarity: 257/584 - (44%)
• Gaps: 106/584 - (18%)

  Fly    40 RFRLLTIDRLAHNRLSIEENANEFNSLEIRRFVASLSGSPKVTSAYGVLGFVRFLEGYYLLLVTK 104
            :|.:...|..|.:.|.|:..:.|. :|.:::.|..   |......:|:||.:..:.|.||:::||
Mouse    17 KFYVEACDDGADDVLIIDRVSTEV-TLAVKKDVPP---SAVTRPIFGILGTIHLVAGNYLVVITK 77

  Fly   105 RKCCAHIGRHLVYTIKD-------TVMVRVNEVTSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSY 162
            :........|.|:...|       ..|:.:.::..|     ....:..|..::.....||||.:|
Mouse    78 KMKVGECFNHAVWRATDFDVLSYKKTMLHLTDIQLQ-----DNKTFLAMLNHVLSMDGFYFSTTY 137

  Fly   163 DLTRTLQYNESAPRYVGAKVDLDRDEPLPDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLLQ 227
            |||.|||                          ..||.....:.:....|:|  :|||||.:||:
Mouse   138 DLTHTLQ--------------------------RLSNTSPEFQEMSLLERAD--QRFVWNGHLLR 174

  Fly   228 PMEG-IMLKDWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVE 291
            .:.. ..:..:.|.|.|||::....||.|::.:..|::|||...||.|:..||.:.:|..||.||
Mouse   175 ELSAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVE 239

  Fly   292 TEQIVSDGQRICAFTQMRGSIPSHWSQDIS-KMVPKPQIQ--LDICDPYAQTPSLHFERLLFHYG 353
            |||||.......:|.|.|||||..|||..: |..|.|||.  .:..|.:.:    ||:..:..||
Mouse   240 TEQIVHYSGNRASFVQTRGSIPIFWSQRPNLKYKPHPQISKVANHMDGFQR----HFDSQVIIYG 300

  Fly   354 APLIMLNLVKKRERRK-----HESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQSRLSGGNV 413
            ..:| :|||..:...|     ..:::|......|||             |.||..::.:    |:
Mouse   301 KQVI-INLVNHKGSEKPLEQTFANMVSSLGSGMIRY-------------IAFDFHKECK----NM 347

  Fly   414 -MEQLAIHAESIVQM----TGMFFKAAGSEPGLQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQL 473
             .::|:|..:.:.:|    :.....:||.....|.|:.|:||:|||||||..|..:.:.:|..||
Mouse   348 RWDRLSILLDQVAEMQDELSYFLVDSAGKVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQL 412

  Fly   474 ERLGFVK-SAKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHRIKT-YRKTAPWGSQG--SDV 534
            :|||.:. ..|||...:.....:|.:.::.:..|.||.|:   ..:|| :.:|......|  .|.
Mouse   413 QRLGVLHVGQKLEEQDEFEKTYKNAWADNANACAKQYAGT---GALKTDFTRTGKRTQLGLLMDG 474

  Fly   535 MQTLSRYYSNTFSDTEKQHSINLFLGIYKPSLTKQGPPIWELQTDYDMHNAFVPRADSKAITDW 598
            ..:|.|||.|.|||..:|.||:||||.|.....:...|:            .|||       ||
Mouse   475 FNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPL------------SVPR-------DW 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	Syja_N	85..407	CDD:460545	95/337 (28%)
Sacm1l	NP_001344414.1	Syja_N	58..345	CDD:460545	95/337 (28%)