DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FIG4 and SAC8

DIOPT Version :9

Sequence 1:	NP_608841.1	Gene:	FIG4 / 33658	FlyBaseID:	FBgn0031611	Length:	858	Species:	Drosophila melanogaster
Sequence 2:	NP_190751.2	Gene:	SAC8 / 824346	AraportID:	AT3G51830	Length:	588	Species:	Arabidopsis thaliana

Alignment Length:	543	Identity:	156/543 - (28%)
Similarity:	251/543 - (46%)	Gaps:	99/543 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 TIDRLAHNRLSIEENANEFNSLEIRRFVASLSGSP-KVTSAYGVLGFVRFLEGYYLLLVTKRKCC 108
            :::|...|...::|||:              |||| :|::.|||.|.:|.|.|.|||::|.|:
plant    38 SVNRRDGNIKPLDENAS--------------SGSPTRVSTIYGVGGTIRLLAGTYLLVITSRE-- 86

  Fly   109 AHIGRHL---VYTIKDTVMVRVNE----VTSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSYDLTR 166
             .:|..|   ::.:.....:..||    .|:|.  ...|..::.:.|.::.....||||..|||.
plant    87 -EVGNFLGLPIFRVTAMKFLPCNEALRFATAQE--KKDETYFRTLLQALETTPGLYFSYETDLTL 148

  Fly   167 TLQYNESAPRYVGAKVDLDRDEPLPDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLLQPMEG 231
            .||               .|.:....||           |.....::|  .|:|||.:||:.:..
plant   149 NLQ---------------RRCKLAEGWN-----------RKPMWKQAD--PRYVWNWHLLEDLIE 185

  Fly   232 IMLKDWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIV 296
            ..|..:::.:..|....:.:.:......|.:::||.:|..|||..:||||.:||.||.||:||||
plant   186 CKLDGFIIPILQGSYQVAELKLKNSPAVVSIMSRRCTRRLGTRMWRRGANLEGDAANFVESEQIV 250

  Fly   297 SDGQRICAFTQMRGSIPSHWSQ--DISKMVPKPQIQLDICDPYAQTPSL---HFERLLFHYGAPL 356
            .......:..|:|||||..|.|  |:|.   ||::::   :.:.:||.:   ||..|...||.
plant   251 EINGFKFSLLQVRGSIPLLWEQIVDLSY---KPRLKI---NKHEETPKVVQRHFHDLCQRYGE-- 307

  Fly   357 IMLNLVKKRERRKHESIISK----ELEYSIRYLNQFLPPPHRMKHIHFDMARQSRLSGGNVMEQL 417
              :..|...::...|..:||    |:|.        ||.   ::::.||.   .::.|....:.|
plant   308 --IMAVDLTDQHGDEGALSKAYATEMEK--------LPD---VRYVSFDF---HQVCGTTNFDNL 356

  Fly   418 AIHAESI---VQMTGMFFKAAGSEPGL--QTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLG 477
            .:..|.|   .:..| :|.....|..|  |.|::|:||:|||||||..|..:|:.:|..||:|:|
plant   357 GVLYEQIGDEFEKQG-YFLVDADENILEEQKGVIRSNCIDCLDRTNVTQSFMGQKSLNLQLQRIG 420

  Fly   478 FVKSAKL--EFDSDCVTMLENLYEEHGDTLALQYGGS-QLVHRIKTYRKTAPWGSQGSDVMQTLS 539
            ...|.:.  .|:.| .|....::.|.||.::|||.|: .|...:..|.|....|:. .|.:..:|
plant   421 VCDSTECISTFEDD-YTKFRTIWAEQGDEVSLQYAGTYALKGDLVRYGKQTMTGAI-KDGLSAMS 483

  Fly   540 RYYSNTFSDTEKQHSINLFLGIY 562
            |||.|.|.|..:|.:::|..|.|
plant   484 RYYLNNFQDGVRQDALDLISGRY 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	COG5329	19..599	CDD:227637	156/543 (29%)
FIG4	NP_608841.1	Syja_N	85..407	CDD:280532	92/337 (27%)
SAC8	NP_190751.2	Syja_N	65..348	CDD:280532	92/339 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5329
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820