Protein Alignment FIG4 and sacm1la

DIOPT Version :9

• Sequence 1: NP_608841.1
• Gene: FIG4 / 33658
• FlyBaseID: FBgn0031611
• Length: 858
• Species: Drosophila melanogaster
• Sequence 2: NP_001038343.2
• Gene: sacm1la / 558940
• ZFINID: ZDB-GENE-060503-122
• Length: 586
• Species: Danio rerio
• Alignment Length: 599
• Identity: 167/599 - (27%)
• Similarity: 266/599 - (44%)
• Gaps: 125/599 - (20%)

  Fly    13 LISSIQKVVLYETRARLYLV----GSNNRETRFRLLTIDRLAHNRLSIEENANEFNSLEIRRFVA 73
            :.::.::..|:.|..:.|:.    |:::      :|.|||:               |.|:
Zfish     1 MANAYERFNLHSTPEKFYIEACDDGADD------VLVIDRV---------------STEM----- 39

  Fly    74 SLSGSPKVTSA------YGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVY--------TIKDTVM 124
            :|:|...:..:      .||:|.||.:.|.||:::|:::....:..|.|:        :.|.|::
Zfish    40 TLAGIKDIPPSGITRPICGVMGTVRLVAGMYLIVITRKRKVGDLFGHTVWKAVEFDVISYKKTIL 104

  Fly   125 VRVNEVTSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQ--YNESAPRYVGAKVDLDRD 187
             .:.::..|     ....:..|..|:.....|||...||||.|.|  .|.|
Zfish   105 -HLTDIQMQ-----DNKTFLTMINNVLNTDGFYFCTDYDLTHTQQRLSNTS-------------- 149

  Fly   188 EPLPDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLL-----QPMEGIMLKDWLLEVTHGFVS 247
               ||:..::     ..||.|        :||:||..||     ||    .|..:...|.|||:.
Zfish   150 ---PDFQEMS-----LLERAD--------QRFMWNGNLLREIIAQP----ELHKFAFPVIHGFIV 194

  Fly   248 QSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSDGQRICAFTQMRGSI 312
            .....|.|:.....:::|||...||.|:..||.:.:|..||.|||||||.......:|.|.||||
Zfish   195 MKPCCINGKVFEWIIISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVQFNNARASFVQTRGSI 259

  Fly   313 PSHWSQDIS-KMVPKPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNLVKKR------ERRKH 370
            |..|||..: |..|||.|..|  ..:......|||..:..||..:| ||||.::      |:...
Zfish   260 PFFWSQRPNLKYKPKPLISKD--TNHMDGLRRHFESQVLIYGKQVI-LNLVNQKGSELPLEQAFA 321

  Fly   371 ESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQ-SRLSGGNVMEQLAIHAESIVQMTGMFFKA 434
            :.:.|.|        |.|:      |:|.||..:: |::....:  |:.:.|.|.:|....:|..
Zfish   322 KMVSSME--------NGFI------KYIAFDFHKECSKMRWHRL--QILVDAVSDMQEEFGYFMV 370

  Fly   435 A--GSEPGLQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVK-SAKLEFDSDCVTMLEN 496
            :  |.....|:|..|:||:|||||||..|..:.:.:|..||:|:|.:. ..|:|..:|...:.:|
Zfish   371 SSDGKVLSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQSQLQRMGVLHVGQKIEEQADFEKIYKN 435

  Fly   497 LYEEHGDTLALQYGGSQLVHR--IKTYRKTAPWGSQGSDVMQTLSRYYSNTFSDTEKQHSINLFL 559
            .:.::.:..|.||.|:..:..  .:|.::| .||.. .|...::.|||.|.|||..:|.||:|||
Zfish   436 AWADNANACAKQYAGTGALKTDFTRTGKRT-HWGLV-MDGWNSMIRYYKNNFSDGFRQDSIDLFL 498

  Fly   560 GIYKPSLTKQGPPI 573
            |.|....|....|:
Zfish   499 GNYSVDETDSLTPL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	COG5329	19..599	CDD:227637	167/593 (28%)
		Syja_N	85..407	CDD:280532	100/344 (29%)
sacm1la	NP_001038343.2	COG5329	56..526	CDD:227637	155/518 (30%)
		Essential for phosphatidylinositol-4-phosphate phosphatase activity. /evidence=ECO:0000250|UniProtKB:Q9NTJ5	451..586		22/64 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5329
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820