Protein Alignment FIG4 and Sac1

DIOPT Version :10

• Sequence 1: NP_608841.1
• Gene: FIG4 / 33658
• FlyBaseID: FBgn0031611
• Length: 858
• Species: Drosophila melanogaster
• Sequence 2: NP_612087.1
• Gene: Sac1 / 38137
• FlyBaseID: FBgn0283500
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 165/560 - (29%)
• Similarity: 259/560 - (46%)
• Gaps: 89/560 - (15%)

  Fly    43 LLTIDRLAHNRLSIEENANEFNSLEIRRFVASLSGSPKVTSAYGVLGFVRFLEGYYLLLVTKRKC 107
            ||.|.|  |::::..:.|:       ...||:|..:.::.   ||||.:..|...|||:.|.|..
  Fly    32 LLVIGR--HDKVTRVQPAS-------GGLVANLRPTRRIC---GVLGTIHLLSCDYLLVATHRLF 84

  Fly   108 CAHIGRHLVYTIKDTVMVRVNEVTSQRPPHPHEDRYKRMF-QNIDLRSNFYFSYSYDLTRTLQYN 171
            ...:...:|:.:....::.....:.||   ...:.|.|:. |.:|.:. |||||.||||.:||..
  Fly    85 VGVLNGAVVWRLAGYDIIPYIPNSFQR---KENENYLRLLRQTLDTKF-FYFSYRYDLTNSLQRQ 145

  Fly   172 ----ESAPRYVGAKVDLDRDEPLPDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLLQPMEGI 232
                :|.|...|.   |.|.|                            :|||||.|:|:.....
  Fly   146 REVAQSRPEVSGL---LQRAE----------------------------QRFVWNGYVLRQFNCD 179

  Fly   233 MLKDWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVS 297
            .::.:.|.:..||||.:.:.|.|:.....::.|||.:.||||...||::.||.|||.|||||||.
  Fly   180 KMEKFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVETEQIVE 244

  Fly   298 DGQRICAFTQMRGSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNLV 362
            ...::..|.|.|||:|.||.| :..:..||:..|.....:.....|||:..:..||.. :.:|||
  Fly   245 FNGQLTGFVQTRGSMPFHWHQ-LPNLRYKPRPVLVPGKDHLAACGLHFKEQIRLYGNN-VAVNLV 307

  Fly   363 KKRERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDM---ARQSRLSGGNVMEQLAIHAESI 424
                  .|:. ...|||.:...|.:.:..| ::::..||.   .|:.|....|::.....|.:..
  Fly   308 ------DHKG-AEGELEATYARLVREMGNP-QVRYESFDFHSECRKMRWDRLNILIDRLAHEQDQ 364

  Fly   425 VQMTGMFFKAAGSEPGLQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVK-SAKLEFDS 488
            ..:..:|  ..|.....|||:.||||:|||||||..|..:.:.:|...|::||.:. ..|:|..|
  Fly   365 FGVYHVF--DDGKLVSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHAS 427

  Fly   489 DCV-TMLENLYEEHGDTLALQYGGSQLVHRIKT-YRKTAPWGSQGS--DVMQTLSRYYSNTFSDT 549
            |.. ::.:.::.::.|.::|||.|:   ..:|| :.:|......|:  |...:|.|||.|.|:|.
  Fly   428 DIFESIFKGVWADNADLVSLQYSGT---CALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNFADG 489

  Fly   550 EKQHSINLFLGIY-----------KPSLTKQGPPIWELQT 578
            ::|.||:||||.|           .|..:|.|   |...|
  Fly   490 QRQDSIDLFLGKYLVNDNEGGAVPSPLESKHG---WRFFT 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	Syja_N	85..407	CDD:460545	98/329 (30%)
Sac1	NP_612087.1	COG5329	3..566	CDD:227637	165/560 (29%)