Protein Alignment FIG4 and fig4

DIOPT Version :10

• Sequence 1: NP_608841.1
• Gene: FIG4 / 33658
• FlyBaseID: FBgn0031611
• Length: 858
• Species: Drosophila melanogaster
• Sequence 2: NP_001018284.3
• Gene: fig4 / 3361401
• PomBaseID: SPAC1093.03
• Length: 832
• Species: Schizosaccharomyces pombe
• Alignment Length: 932
• Identity: 284/932 - (30%)
• Similarity: 427/932 - (45%)
• Gaps: 193/932 - (20%)

  Fly     2 NNDNPNIVFNPLISSIQKVVLYETRARLYLVGSNNRETRFRLLTI----DRLAHNRLSIEENANE 62
            |:|.|.:.|.          ||:.:...|:|..|...|.||:|.|    |.|:   :||||.|..
pombe     5 NSDEPLVKFE----------LYQLKKCYYIVSENATATIFRILKITQSEDELS---ISIEEAAKI 56

  Fly    63 FNSLEIRRFVASLSGSPK------VTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKD 121
            ....:::.::..|.....      ||.||.:||..||..||||.|.|:||..|.||.|.||.:..
pombe    57 LFRQKLQLYLEKLENESADGKLILVTKAYAILGLFRFTAGYYLYLCTERKVVAVIGGHNVYHVDK 121

  Fly   122 TVMVRVNEVTSQRPPHPHEDRYKR----MFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGAKV 182
            |..:.:|      |...|....:|    ..:.:||...|||||||||::|:||..:
pombe   122 TQFIELN------PSRRHNTSVERKCMSSIEKVDLARTFYFSYSYDLSQTIQYGFT--------- 171

  Fly   183 DLDRDEPLPDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLLQP-MEGIML-KDWLLEVTHGF 245
                 .|:|.           |:         .|..||||..:|:| ::.:.: ..|.:.:.|||
pombe   172 -----HPIPQ-----------HQ---------VRDMFVWNWNMLRPILDSVGIDSPWCIPLIHGF 211

  Fly   246 VSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSDGQR--------- 301
            |.|:.:|::|:.:.|.|:||||..|||.|||:||....|.|||||||||||.||..
pombe   212 VDQAKLSVYGKPIIVTLIARRSRHFAGARFLRRGIRDDGYVANEVETEQIVFDGSASSFPISSTT 276

  Fly   302 -----ICAFTQMRGSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNL 361
                 ..::.|.|||||..|||:.|.:.|||.|.:|..||:..:.:|||:||..|||.|.|:|||
pombe   277 PGIPCYTSYVQHRGSIPLRWSQEFSNITPKPPIGIDFHDPFYASTALHFDRLFGHYGIPCIVLNL 341

  Fly   362 VKKRERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDM--ARQSRLSGGNVMEQLAIHAESI 424
            ||..|:.|.||::..|.|.:|:||||||....::::|.:||  |.:.::.....:||:   |..|
pombe   342 VKSSEKVKRESLLLDEFESAIQYLNQFLKDSQKIQYIAWDMSAASKKKVPVTKTLEQM---ASDI 403

  Fly   425 VQMTGMFFKAAGSEPG-LQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKLEFDS 488
            |:.||.|..|....|| .|||:|||||||||||||:|||.||||.|..||..||.:.|.:|:::|
pombe   404 VKKTGFFCTADRFFPGTFQTGVVRTNCVDCLDRTNAAQFVIGKCVLAAQLRALGVLDSPQLDYES 468

  Fly   489 DCVTMLENLYEEHGDTLALQYGGSQLVHRIKTYRKTAPWGSQGSDVMQTLSRYYSNTFSDTEKQH 553
            |.|.:|..:|..|||.:|||||||.||:.:.||||...|.|...|:::::.|:|||:|.|.::|.
pombe   469 DAVRLLAEMYHGHGDAIALQYGGSLLVNTLDTYRKNNQWSSTSRDLIESVKRFYSNSFVDFQRQE 533

  Fly   554 SINLFLGIYKPSLTKQGPPIWELQTDYDMHNAFVPRADSK--AITD------------------- 597
            :|:||||                  ::.:|...|...:.:  |:|:
pombe   534 AISLFLG------------------NFTVHGKIVVFGEKRLQALTEKFKNGQLVRRDYRYWWTPV 580

  Fly   598 WVRHKVRACLPYSCADSNKLVKELFRVHSSGLEM-IDAYSNYHQSFKWTDFSE----HIAFEISQ 657
            :|..::| |....| ||         :...|::. .:.:.|.:.....:.|||    ::...::.
pombe   581 YVNQELR-CKNAYC-DS---------IQRKGIKFPANYFDNVYTPNSISSFSEVLLPNLISTLNF 634

  Fly   658 LALRYMPTFRTNFSPFQRQIQTSRKARQNPSMTGQSSTGSMNSNSSSSSEGDDSSSDEELSA--- 719
            ..|..:|..|.:|.|.............||.:..::....|...|:.....|:...|::...
pombe   635 APLSLIPLLRKSFLPLSYNGFGIEAPSLNPFIPRRNQPRDMFKTSAEEENEDEDEDDDKFRRVSL 699

  Fly   720 -------------SFAEKEANQTESTEPAAATLATGLPSMEEIYGCTINPPS----KQSMAVYKK 767
                         .|..|..:|              :|...::.......|.    ...:.|||.
pombe   700 YKWLFNNEERPVHKFIRKRLHQ--------------IPVSNKVQPRDQKQPDFKIPNTDINVYKI 750

  Fly   768 YVQMGKLSSGGARPAQTAVAQRDQELAKIMRGITLRPLSDYGTDSYLSVRPPVVPRKSLTIYAEY 832
            :.|...:|  |.....|.:::.|:.:        ....:||..|....::     .|.|..|.:|
pombe   751 HFQYNNIS--GLADNYTLLSKHDRAM--------YNNYADYSPDKIKEIK-----EKELNTYNDY 800

  Fly   833 CRTRSTFNAVPKLEEFDVLYQY 854
            ..:..:.|...|.:..:.:..|
pombe   801 FNSAISENPTLKSDRSEKVAFY 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	Syja_N	85..407	CDD:460545	133/343 (39%)
fig4	NP_001018284.3	Syja_N	85..387	CDD:460545	133/341 (39%)