DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FIG4 and Ocrl

DIOPT Version :9

Sequence 1:	NP_608841.1	Gene:	FIG4 / 33658	FlyBaseID:	FBgn0031611	Length:	858	Species:	Drosophila melanogaster
Sequence 2:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster

Alignment Length:	402	Identity:	80/402 - (19%)
Similarity:	138/402 - (34%)	Gaps:	148/402 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   537 TLSRYYSN------TFSDTEKQHS---------INLF--LGIYKPSLTKQGPPIWELQTDYDMHN 584
            |.|.:|..      :|..|..||.         :|.:  :|..|..|.|:       :::|.::.
  Fly   126 TESHHYEEFVAKVISFKSTMAQHDPETVLNFRWLNDYRQIGEVKQELKKR-------ESEYIVYK 183

  Fly   585 AFVPRADSKAITDW-VRHKVRACLPYSCADSNKLVKELFR-------VHSSGLEMID----AYSN 637
            ..:...     ..| |.:|       :|:|||..::....       :::.||:.:|    |..|
  Fly   184 DIIIYC-----ATWNVNNK-------TCSDSNNPLRAWLACSEKPPDIYAIGLQELDTPTKAMLN 236

  Fly   638 YHQ----SFKWTD---FSEH--IAFEISQLALRYMPTFRTNFSPFQRQIQTSRKARQN-----PS 688
            ..|    ..:|.|   .|.|  :.:|| .::.|.:.|..|        :...::.||:     |.
  Fly   237 STQVQAIEKQWIDKMMDSVHPDVEYEI-LMSHRLVATMLT--------VIVRKQLRQHIIRCRPK 292

  Fly   689 MTGQSSTGSMNSN-----SSSSSEGDDSSSDEELSASFA-EKEANQTESTEPAAATLATGLPSME 747
            ...:....::.:.     |...:||:....:..|:|... .:|.||..:      .:..|:...:
  Fly   293 SVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYN------AIVEGIRFDD 351

  Fly   748 EIYGCTIN-----------------PPSKQSMAVYKKYVQMGKLSSGGARPAQT--AVAQRDQEL 793
               |.||:                 ||.:|         :.|.||.     |||  .:.|.||..
  Fly   352 ---GRTISDHDHIFWVGDLNYRIQEPPGQQ---------RPGPLSD-----AQTYELLLQYDQLR 399

  Fly   794 AKIMRG----------ITLRPLSDY--GTDSYLSVRPPVVPRKSLTIYAEYC------RTR---S 837
            .::.||          |..||...|  |||:|.|......|        .||      .||   .
  Fly   400 QEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAP--------AYCDRVLWKGTRIEQL 456

  Fly   838 TFNAVPKLEEFD 849
            .:|::.::.:.|
  Fly   457 AYNSIMEIRQSD 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	COG5329	19..599	CDD:227637	14/79 (18%)
FIG4	NP_608841.1	Syja_N	85..407	CDD:280532
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622	8/36 (22%)
		INPP5c_INPP5B	185..478	CDD:197327	67/336 (20%)
		RhoGAP_OCRL1	614..823	CDD:239845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447397
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930