Protein Alignment FIG4 and sac-1

DIOPT Version :9

• Sequence 1: NP_608841.1
• Gene: FIG4 / 33658
• FlyBaseID: FBgn0031611
• Length: 858
• Species: Drosophila melanogaster
• Sequence 2: NP_492518.2
• Gene: sac-1 / 172778
• WormBaseID: WBGene00009264
• Length: 598
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 164/595 - (27%)
• Similarity: 272/595 - (45%)
• Gaps: 124/595 - (20%)

  Fly    13 LISSIQKVVLYETRARLYLVGSNNRETRFRLLTID----RLAHNRLSIEENANEFNSLEIRRFVA 73
            ::.|:..:.:||: ..||     :...:|.|...|    ..:.:.|.|:.:.|....::.|:...
 Worm     1 MVDSLLSMDIYES-FNLY-----SHPEKFFLEPTDLGGGAASKHYLEIDRHTNVMKIIDSRKQRV 59

  Fly    74 SLSGSPKVTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVNEVTSQRPPHP 138
            .::.: .:...||:||.::.:.||.|:::||......:..|.::||:|..::...:.|.    |.
 Worm    60 PIADT-DIKFIYGILGTIKLVSGYALIVITKASLIGQVNNHNIWTIQDAEIIPYKKTTL----HL 119

  Fly   139 HED--RYKRMFQNIDLR----SNFYFSYSYDLTRTLQYNESAPRYVGAKVDLDRDEPLPDWNTLT 197
            .|.  ||.|:|.::...    ..||:|.:.|::||.|:.:              :..:|.:.| .
 Worm   120 TEKQIRYNRLFTDMLTHVLSIGGFYYSTTLDISRTFQWLQ--------------ENAVPLFKT-R 169

  Fly   198 SNVDKAHERVDYAFRSDSRKRFVWNAYLLQPMEGIM-LKDWLLEVTHGFVSQSCISIFGRHVNVC 261
            |.:|:|.|            ||:||.:||..:..:. .:.:.|.|.|||:.|:.:::.|:.:.:.
 Worm   170 SMLDRASE------------RFIWNGHLLSQIRQVPGAERYTLPVIHGFIGQNRVNVNGKEIKLT 222

  Fly   262 LVARRSSRFAGTRFLKRGANFQGDVANEVETEQIV---SDGQRICAFTQMRGSIPSHWSQDISKM 323
            :::|||...||.||.|||.:..|..||.|||||||   :..:.:.:|.|:|||||..|:|
 Worm   223 IISRRSIYRAGVRFYKRGVDVDGHAANFVETEQIVEYTNPDKHLTSFVQLRGSIPLLWTQ----- 282

  Fly   324 VPKPQIQLDICDPYAQTPSLH--------FERLLF----HYGAPLIMLNLVKKRERRKHESIISK 376
              ||.::      :...|:|.        |.|...    |||...:::|||.::.|.|.   :..
 Worm   283 --KPNLR------WQPMPTLKPTDDQLAAFNRAFSWHKQHYGGKHVIVNLVNQKGREKK---VGG 336

  Fly   377 ELEYSIRYLN---------QFLPPPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESIVQMTGMFF 432
            |||...|..|         .|....|.|:....|:.|          |||:....|.    |.|:
 Worm   337 ELERISRQANIEFVRYHQFDFHKECHSMQWHRIDLLR----------EQLSQEISSF----GYFY 387

  Fly   433 KAAGS--EPGLQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKLEFDSDCVTMLE 495
            .:..|  ....|.|..||||:|||||||..|..:.:.:|..||..||.:.|.:...|   :.:||
 Worm   388 LSPNSMETSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQLRMLGILYSEQKVQD---IPLLE 449

  Fly   496 N----LYEEHGDTLALQYGGSQLV------HRIKTYRKTAPWGSQGSDVMQTLSRYYSNTFSDTE 550
            :    ::.::||..:.||.|:..:      |..:||     .|:. .|.:..:|||..|.|.|..
 Worm   450 DAFKQMWADNGDECSRQYAGTGALKADFTRHGRRTY-----VGAM-KDGVNAVSRYVRNNFGDGY 508

  Fly   551 KQHSINLFLG 560
            :|.||:||||
 Worm   509 RQDSIDLFLG 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_608841.1	COG5329	19..599	CDD:227637	163/589 (28%)
		Syja_N	85..407	CDD:280532	99/352 (28%)
sac-1	NP_492518.2	COG5329	69..575	CDD:227637	152/520 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5329
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820