DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15436 and ZNF551

DIOPT Version :9

Sequence 1:NP_608840.1 Gene:CG15436 / 33657 FlyBaseID:FBgn0031610 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_612356.2 Gene:ZNF551 / 90233 HGNCID:25108 Length:670 Species:Homo sapiens


Alignment Length:337 Identity:110/337 - (32%)
Similarity:165/337 - (48%) Gaps:47/337 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 GDLFSEMICPQCYEDVKSAYGIRQTCEESHQ-------FYCRVRDEGIEDALCALLE------EE 95
            |.|:.   |.:|    :.|:..:.|..:..|       |.|...:|........:|.      |.
Human   248 GGLYE---CSKC----EKAFTCKNTLVQHQQIHTGQKMFECSECEESFSKKCHLILHKIIHTGER 305

  Fly    96 DWEISEDEDARIDSAS--------------AADDDGKSDSKKV-------------AFECRECHK 133
            .:|.|:.|.|.|..:.              ...:..|:.|.|.             .:||.||.|
Human   306 PYECSDREKAFIHKSEFIHHQRRHTGGVRHECGECRKTFSYKSNLIEHQRVHTGERPYECGECGK 370

  Fly   134 KYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKTFAQQSTLQ 198
            .:::..:..||.|.|...:.:.|..|.::||....|..|.:.|....||:||.|.|:|:.:|.|.
Human   371 SFRQSSSLFRHQRVHSGERPYQCCECGKSFRQIFNLIRHRRVHTGEMPYQCSDCGKSFSCKSELI 435

  Fly   199 SHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTGE 263
            .|:|.|:||||::|.:|.|:|.:.|:|.||...|..:||::||:|.|:|:|||.|..|.|.||||
Human   436 QHQRIHSGERPYECRECGKSFRQFSNLIRHRSIHTGDRPYECSECEKSFSRKFILIQHQRVHTGE 500

  Fly   264 RPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCA 328
            ||::||.|.|:|..|..|.||.|:|...||:.||.|.|:||..|.|.:|:.:|..||.::|..|.
Human   501 RPYECSECGKSFTRKSDLIQHRRIHTGTRPYECSECGKSFRQRSGLIQHRRLHTGERPYECSECG 565

  Fly   329 SFYKQRKTLARH 340
            ..:.|..:|.:|
Human   566 KSFSQSASLIQH 577

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15436NP_608840.1 zf-AD 4..78 CDD:285071 8/40 (20%)
C2H2 Zn finger 128..148 CDD:275368 7/19 (37%)
C2H2 Zn finger 156..176 CDD:275368 6/19 (32%)
COG5048 <180..341 CDD:227381 74/161 (46%)
C2H2 Zn finger 184..204 CDD:275368 9/19 (47%)
zf-H2C2_2 197..219 CDD:290200 11/21 (52%)
C2H2 Zn finger 212..232 CDD:275368 8/19 (42%)
zf-H2C2_2 224..249 CDD:290200 11/24 (46%)
C2H2 Zn finger 240..260 CDD:275368 11/19 (58%)
zf-H2C2_2 252..276 CDD:290200 13/23 (57%)
C2H2 Zn finger 268..288 CDD:275368 10/19 (53%)
C2H2 Zn finger 296..316 CDD:275368 9/19 (47%)
C2H2 Zn finger 324..341 CDD:275368 5/17 (29%)
ZNF551NP_612356.2 KRAB 29..>71 CDD:214630
KRAB 29..68 CDD:279668
C2H2 Zn finger 253..273 CDD:275368 5/23 (22%)
COG5048 279..624 CDD:227381 103/299 (34%)
C2H2 Zn finger 281..301 CDD:275368 3/19 (16%)
C2H2 Zn finger 311..329 CDD:275368 3/17 (18%)
C2H2 Zn finger 337..357 CDD:275368 3/19 (16%)
zf-H2C2_2 349..374 CDD:290200 5/24 (21%)
C2H2 Zn finger 365..385 CDD:275368 7/19 (37%)
zf-H2C2_2 377..402 CDD:290200 7/24 (29%)
C2H2 Zn finger 393..413 CDD:275368 6/19 (32%)
zf-H2C2_2 405..430 CDD:290200 10/24 (42%)
C2H2 Zn finger 421..441 CDD:275368 9/19 (47%)
zf-H2C2_2 433..458 CDD:290200 12/24 (50%)
C2H2 Zn finger 449..469 CDD:275368 8/19 (42%)
zf-H2C2_2 461..486 CDD:290200 11/24 (46%)
C2H2 Zn finger 477..497 CDD:275368 11/19 (58%)
zf-H2C2_2 490..514 CDD:290200 14/23 (61%)
C2H2 Zn finger 505..525 CDD:275368 10/19 (53%)
zf-H2C2_2 517..542 CDD:290200 12/24 (50%)
C2H2 Zn finger 533..553 CDD:275368 9/19 (47%)
zf-H2C2_2 546..570 CDD:290200 7/23 (30%)
C2H2 Zn finger 561..581 CDD:275368 5/17 (29%)
zf-H2C2_2 573..598 CDD:290200 2/5 (40%)
C2H2 Zn finger 589..609 CDD:275368
C2H2 Zn finger 617..637 CDD:275368
zf-H2C2_2 629..654 CDD:290200
C2H2 Zn finger 645..665 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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